Clinical Cholesterol/Anti-Homocysteine Support
98/100
This product looks safe
- Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
- 53% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
Label Data
2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
53%
Evidence Coverage
Supplement Facts — Evidence Check
Oat Bran 10% Beta Glucan
600 mg
500 mg
📊 Market median: 496.0mg (192 products)
📚 20 studies — no high-quality reviews
400 mg
📊 Market median: 250.0mg (337 products)
📚 125 studies (Tier A: 1, B: 41)
Phytosterols 90%
250 mg
100 mg
📊 Market median: 500.0mg (497 products)
📚 132 studies (Tier A: 0, B: 40)
Gum Guggul 2.5%
100 mg
Allium cepa
80 mg
80 mg
(400% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.3× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
Vitamin C
60 mg
(100% DV)
Artichoke
50 mg
40 mg
📊 Market median: 100.0mg (284 products)
📚 10 studies (Tier A: 0, B: 4)
25 mg
(1250% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
20 mg
📊 Market median: 167.0mg (311 products)
📚 182 studies (Tier A: 0, B: 65)
Policosanols
10 mg
400 mcg
(100% DV)
✅ Within RDA (1.0× RDA of 0.4 mg)
📚 225 studies (Tier A: 10, B: 105)
250 mcg
(4167% DV)
📊 104.2× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
120 mcg
(100% DV)
📊 3.4× RDA — above typical dose
📚 197 studies (Tier A: 1, B: 55)
Other Ingredients
All Natural Vegetable Source of
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (100% of products)
Structure/Function (82% of products)
Nutrient (8% of products)
Target Groups
Adult (18 - 50 Years)
Product Information
📋 Directions for Use
Directions: Take two capsules twice daily with 4 oz. of pure water.
Additional Information
PATENT PENDING CLINICAL GRADE FORMULATION
Product Details
UPC / SKU
0 36733 00821 1
DSLD Entry Date
2013-02-25
Product Type
Other Combinations
Form
Capsule
Brand
Natural Clinician
DSLD ID
18607
Data Updated
2026-04-11
Research Evidence
23
Research Sources
47
Avg Quality Score
18
Rct
3
Systematic Review
1
Meta Analysis
1
Clinical Trial
B
Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
C
Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
C
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
C
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
C
Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
C
Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
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