Clinical Cholesterol/Anti-Homocysteine Support
98/100
This product looks safe
- Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
- 53% of ingredients have research evidence
C
Label Compliance Grade
What the Evidence Says
AI-generated · Qwen 3.6 · methodologyOat bran beta-glucans and phytosterols have strong evidence for reducing LDL cholesterol levels. Trimethylglycine is used to support homocysteine metabolism, while ginger and garlic provide moderate support for cardiovascular health. The ingredient profile is associated with a high safety score.
AI-generated summary based on research evidence. Not medical advice.
Alerts
Safety Alerts
Niacin: 80mg is 2.3× the Tolerable Upper Intake Level (35mg)
Label
Product Label
Details
Label Data
2 Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
53%
Evidence Coverage
Ingredients
Supplement Facts — Evidence Check
Oat Bran 10% Beta Glucan
600 mg
500 mg
Market median: 496.0mg (192 products)
20 studies — no high-quality reviews
400 mg
Market median: 250.0mg (337 products)
127 studies (A:1, B:41)
Phytosterols 90%
250 mg
100 mg
Market median: 500.0mg (497 products)
135 studies (A:0, B:40)
Gum Guggul 2.5%
100 mg
Allium cepa
80 mg
80 mg
(400% DV)
Exceeds UL by 2.3× (UL: 35 mg)
196 studies (A:5, B:63)
Vitamin C
60 mg
(100% DV)
Artichoke
50 mg
40 mg
Market median: 100.0mg (284 products)
10 studies (A:0, B:4)
25 mg
(1250% DV)
19.2× RDA — above typical dose (UL: 100 mg)
114 studies (A:3, B:35)
20 mg
Market median: 167.0mg (311 products)
183 studies (A:0, B:65)
Policosanols
10 mg
400 mcg
(100% DV)
Within RDA (1.0× RDA)
226 studies (A:10, B:105)
250 mcg
(4167% DV)
104.2× RDA — above typical dose
139 studies (A:1, B:44)
120 mcg
(100% DV)
3.4× RDA — above typical dose
199 studies (A:1, B:55)
Other Ingredients
All Natural Vegetable Source of
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
Directions: Take two capsules twice daily with 4 oz. of pure water.
Additional Information
PATENT PENDING CLINICAL GRADE FORMULATION
Metadata
Product Details
UPC / SKU0 36733 00821 1
DSLD Entry Date2013-02-25
Product TypeOther Combinations
FormCapsule
BrandNatural Clinician
DSLD ID18607
Data Updated2026-04-11
Research
Research Evidence
23
Research Sources
47
Avg Quality
18
Rct
3
Systematic Review
1
Meta Analysis
1
Clinical Trial
B
Effect of Folic Acid, Betaine, Vitamin B₆, and Vitamin B12 on Homocysteine and Dimethylglycine Levels in Middle-Aged Men Drinking White Wine
C
Betaine for nonalcoholic fatty liver disease: results of a randomized placebo-controlled trial
C
Guidelines for the diagnosis and management of cystathionine beta-synthase deficiency
C
Newborn screening for homocystinurias and methylation disorders: systematic review and proposed guidelines
C
Effects of low-dose B vitamins plus betaine supplementation on lowering homocysteine concentrations among Chinese adults with hyperhomocysteinemia: a randomized, double-blind, controlled preliminary clinical trial
C
Association of Betaine-Homocysteine S-Methyl Transferase (rs3797546 and rs3733890) polymorphisms with non-syndromic cleft lip/palate: A meta-analysis
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
C
Effect of inulin supplementation on fecal and blood metabolome in alcohol use disorder patients: A randomised, controlled dietary intervention.
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.