🟢 97/100

This product looks safe

  • Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • Vanadium: 2.5mg is 1.4× the Tolerable Upper Intake Level (1.8mg)
  • 48% of ingredients have research evidence
D Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
⚠️ Vanadium: 2.5mg is 1.4× the Tolerable Upper Intake Level (1.8mg)

Label Data

28.5 Gram(s) Serving Size
14 Servings
Other Combinations Product Type
48% Evidence Coverage

Supplement Facts — Evidence Check

Calories
190 {Calories}
Total Fat
4 g (6% DV)
Cholesterol
Total Carbohydrates
22 g (7% DV)
Protein
21 g
50 mg (3333% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
40 mg (200% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 40mg UL 35mg
5 mg (250% DV)
📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 5mg UL 100mg
200 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 0.2mg UL 1.0mg
50 mcg (833% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
5000 mcg (1667% DV)
📊 166.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 5.0mg
35 mg (350% DV)
📊 7.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 35mg
150 mcg (100% DV)
✅ Within RDA (1.0× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.15mg UL 1.1mg
15 mg (100% DV)
✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 15mg UL 40mg
500 mcg (417% DV)
📊 14.3× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.5mg
Sodium
350 mg (15% DV)
Potassium
350 mg (10% DV)
Medium-Chain Triglycerides
1 Gram(s)
Brown Seaweed Blend
500 mg
Cinnamon
200 mg
📊 Market median: 260.0mg (249 products) 📚 156 studies (Tier A: 4, B: 61)
This product: 200mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 200mg
2.5 mg
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 1.8 mg) 📚 1 studies (Tier A: 0, B: 1)
This product: 2.5mg UL 1.8mg

Other Ingredients

VegaPro Inulin Cocoa powder evaporated Cane Natural flavors Sunflower Oil Potassium Citrate Sodium Citrate Sodium Chloride Xanthan Gum Guar Gum Stevia leaf extract

Label Claims — Verification

Nutrient
All Other
Structure/Function
All Other (98% of products) Structure/Function (87% of products) Nutrient (16% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

DIRECTIONS: Blend, shake, or briskly stir two level scoops (57 g) of OptiGlycemiX(TM) into 8-12 oz chilled water and consume one to two times daily; or take one to two scoops approximately 30 minutes before each main meal (upper limit of six scoops/day); or use as directed by your healthcare practitioner.

⚠️ Warnings & Precautions

Keep out of reach of children.

Avoid if pregnant or lactating, or if allergic to any ingredient.

• Pharmaceutical Grade • Professional Use Only

CAUTIONS: Consult your healthcare practitioner before use, especially if you are taking blood-sugar-lowering medications or being treated for diabetes.

🧪 Formulation Notes

OptiGlycemiX is a research-based functional food formulated to nutritionally support individuals with insulin/glucose dysregulation and related health issues. It features InSea2(R) - a clinically tested, optimized blend of purified polyphenols from wild-crafted brown seaweed. InSea2 uniquely slows carbohydrate digestion and assimilation and can reduce the impact of high-glycemic foods, resulting in more appropriate glucose and insulin responses. This newly developed, next generation dual carb controller is 100% natural, has an excellent safety profile, and is friendly to the gastrointestinal tract.* OptiGlycemiX also delivers other innovative ingredients, including VegaPro(TM) - a proprietary, sugar-free, sweetener-free, low-allergy-potential source of vegetable protein from pea protein isolate and rice protein concentrate – and CinSulin(R), a concentrated, patented water extract of cinnamon with a potent 10:1 yield ratio. Cinnamon has been studied extensively for its roles in glucose uptake, glycogen synthesis, insulin action, and support for healthy blood lipids. These principal ingredients are complemented by the inclusion of thiamin (as benfotiamine) to boost transketolase activity; alpha-lipoic acid (ALA); green tea leaf extract; vanadium, chromium, and zinc as Albion(R) TRAACS(R) chelates; 5-MTHF (bioactive folate) as Quatrefolic(R); fiber from inulin; and other key vitamins and minerals.* This exclusive combination of well-researched, clinically validated, and highly bioavailable ingredients employs a multi-modal defense against factors that cause blood glucose to rise too quickly, insulin sensitivity to decrease, glycation and oxidative stress to escalate, fat storage to increase, and blood lipids to become altered.*

DOES NOT CONTAIN: Wheat, gluten, corn protein, yeast, soy, animal or dairy products, artificial colors, artificial sweeteners, or preservatives.

Functional Food for Individuals With Insulin/Glucose Dysregualtion Featuring InSea2(R) - Next Generation Carbohydrate Control*

Additional Information

EXCLUSIVE PROFESSIONAL FORMULAS

21g PROTEIN

FUNCTIONAL FOOD

This package is completely recyclable (recycle)

Quatrefolic(TM)

V VegaPro(TM) 100% VEGAN 100% Gluten Free

STORAGE: Keep tightly closed in a cool, dry place.

REV. 100411

Product Details

DSLD Entry Date 2012-02-23
Product Type Other Combinations
Form Powder
Brand XYMOGEN
DSLD ID 5957
Data Updated 2026-04-11

Research Evidence

21 Research Sources
52 Avg Quality Score
13 Rct
4 Meta Analysis
2 Systematic Review
2 Clinical Trial
A Alpha-lipoic acid for diabetic peripheral neuropathy
Systematic Review The Cochrane database of systematic reviews 2024
B Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy
Rct Nutrients 2024
B Alpha Lipoic Acid Supplementation and Iron Homeostasis: A Comprehensive Systematic Review and Meta-Analysis of Randomized Controlled Clinical Trials
Meta Analysis International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 2024
B Effectiveness of alpha-lipoic acid in patients with neuropathic pain associated with type I and type II diabetes mellitus: A systematic review and meta-analysis
Meta Analysis Medicine 2023
C The effects of alpha-lipoic acid supplementation on glucose control and lipid profiles among patients with metabolic diseases: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Metabolism: clinical and experimental 2018
C A systematic review and meta-analysis of α-lipoic acid in the treatment of diabetic peripheral neuropathy
Meta Analysis European journal of endocrinology 2012
C Oral Alpha Lipoic Acid Treatment for Symptomatic Diabetic Peripheral Neuropathy: A Randomized Double-Blinded Placebo-Controlled Study
Rct Endocrine, metabolic & immune disorders drug targets 2020
C A randomized, double-blind, placebo controlled study to evaluate the effect of alpha-lipoic acid on inhibition of ADP-and collagen-induced platelet aggregation ex vivo in diabetic neuropathy patients on gabapentin or pregabalin
Rct Journal of postgraduate medicine 2024
C Ranking Alpha Lipoic Acid and Gamma Linolenic Acid in Terms of Efficacy and Safety in the Management of Adults With Diabetic Peripheral Neuropathy: A Systematic Review and Network Meta-analysis
Systematic Review Canadian journal of diabetes 2024
C Effect analysis of tanshinone IIA sulfonate sodium combined with a-lipoic acid in patients with diabetes peripheral neuropathy.
Rct Pakistan journal of pharmaceutical sciences
View all evidence for Alpha Lipoic Acid →

Compare Similar Products

View all Alpha Lipoic Acid products →