Home/ Supplements/ Vitamin C/ Ultra-Stress Sustained Release

Ultra-Stress Sustained Release

product on market Tablet or Pill NaturesPlus Safety: 91/100
91/100

This product looks safe

  • Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
  • Vitamin B6: 125mg is 1.2× the Tolerable Upper Intake Level (100mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 69% of ingredients have research evidence
F Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins and vitamin C, which are supported by strong evidence for supporting energy metabolism and cellular function during stress. These nutrients play key roles in neurotransmitter synthesis and antioxidant defense. The overall evidence coverage for this specific blend is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)

Vitamin B6: 125mg is 1.2× the Tolerable Upper Intake Level (100mg)

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Ultra-Stress Sustained Release
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
69%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
500 mg (556% DV)
125 mg (10417% DV)
104.2× RDA — above typical dose 76 studies (A:0, B:33)
125 mg (9615% DV)
96.2× RDA — above typical dose 13 studies (A:0, B:1)
125 mg NE (781% DV)
Exceeds UL by 3.6× (UL: 35 mg) 196 studies (A:5, B:63)
125 mg (7353% DV)
Exceeds UL by 1.2× (UL: 100 mg) 114 studies (A:3, B:35)
667 mcg DFE (167% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
500 mcg (20833% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
125 mcg (417% DV)
4.2× RDA — above typical dose 27 studies (A:0, B:11)
200 mg (4000% DV)
40.0× RDA — above typical dose 2 studies — no high-quality reviews
32 mg (6% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
Iron
20 mg (111% DV)
75 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews

Other Ingredients

Hydroxypropyl Methylcellulose Stearic Acid Microcrystalline Cellulose Ferrous Fumarate Magnesium Stearate Rose Hip Soy Protein Isolate Rice Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Directions: One tablet daily, preferably with a meal.

Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a physician or poison control center immediately.

Formulation Notes

B-Complex, Vitamin C & Iron

Stress Support

Additional Information

Peel here

Metadata

Product Details

UPC / SKU0 97467 01229 5
DSLD Entry Date2024-11-22
Product TypeOther Combinations
FormTablet or Pill
BrandNaturesPlus
DSLD ID320536
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.