Eyesyl +BioPerine by Approved Science — Ingredients, Evidence & Safety

🟢 98/100

This product looks safe

Folate: 1667mg is 1667.0× the Tolerable Upper Intake Level (1.0mg)
61% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 1667mg is 1667.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

61% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A

1500 mcg RAE (167% DV)

Vitamin C

100 mg (111% DV)

Vitamin E

180 mg (1200% DV)

📊 12.0× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 180mg UL 1000mg

Vitamin B1

100 mg (8333% DV)

📊 83.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 100mg

Vitamin B6

50 mg (2941% DV)

📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 50mg UL 100mg

Folate

1667 mcg DFE (417% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 1667mg UL 1.0mg

Vitamin B12

1000 mcg (41667% DV)

📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 1.0mg

Selenium

55 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)

RDA 0.055mg This product: 0.055mg UL 0.4mg

Chromium

400 mcg (1143% DV)

📊 11.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)

RDA 0.035mg This product: 0.4mg

Taurine

400 mg

📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)

This product: 400mg

Bilberry Fruit Extract

160 mg

📊 Market median: 100.0mg (120 products)

Median 100.0mg This product: 160mg

Ginkgo biloba, Powder

160 mg

📊 Market median: 120.0mg (440 products) 📚 187 studies (Tier A: 1, B: 71)

This product: 160mg

Black Currant

50 mg

Grape Seed Extract

50 mg

📊 Market median: 100.0mg (284 products) 📚 10 studies (Tier A: 0, B: 4)

This product: 50mg

Opti-Sci Eye Health Complex

22 mg

Quercetin

20 mg

📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)

This product: 20mg

BioPerine

10 mg

AstaZine

4 mg

Other Ingredients

Cellulose Rice Flour

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take two capsules daily, (one in the morning and one in the afternoon), before meals with an 8 oz. glass of water.

⚠️ Warnings & Precautions

Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement. Keep out of reach of children.

🧪 Formulation Notes

Manufactured in the USA according to Good Manufacturing Practice (cGMP) and conforms to the tested ingredients grade, strength and purity of industry Quality Standards.

Vegan friendly

Made with GMO free ingredients

Advanced eye support Premium grade High potency Safe Fast Natural formula Optimal strength GMP Certified

Contains Opti-Sci and AstaZine

100% vegan friendly

Additional Information

Store at room temperature.

Vegan friendly Made in USA No animal testing GMP Good Manufacturing Practice Quality Product

Product Details

UPC / SKU X002X77D27

DSLD Entry Date 2024-11-22

Product Type Other Combinations

Form Capsule

Brand Approved Science

DSLD ID 319753

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →