Hema-Plex Softgels

product on market Softgel Capsule NaturesPlus 🟢 Safety: 96/100
Brand: NaturesPlus
🟢 96/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 50% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

3 Softgel(s) Serving Size
20 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

Calories
10 Calorie(s)
Total Fat
1 Gram(s) (1% DV)
Vitamin C
300 mg (333% DV)
20 mg (133% DV)
✅ 1.3× RDA — within safe limits 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 20mg UL 1000mg
25 mg (2083% DV)
📊 20.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 25mg
25 mg (1923% DV)
📊 19.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 25mg
50 mg NE (313% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
25 mg (1471% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 25mg UL 100mg
667 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 667mg UL 1.0mg
1000 mcg (41667% DV)
📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 1.0mg
25 mg (500% DV)
📊 5.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 25mg
Calcium
25 mg (2% DV)
Iron
85 mg (472% DV)
5 mg (45% DV)
✅ Within RDA (0.5× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 5mg UL 40mg
10 mcg (18% DV)
✅ Within RDA (0.2× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.01mg UL 0.4mg
2 mg (222% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
5 mg (217% DV)
✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 5mg UL 11mg
L-Cysteine
50 mg
Proanthoplex
30 mg
Beet
15 mg

Other Ingredients

Sunflower Oil Gelatin Glycerin Beeswax Lecithin purified Water Natural color Chlorophyllin Spinach Broccoli shattered cell wall Chlorella Spirulina

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Adult (18 - 50 Years) No Allergies Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, three softgels daily.

⚠️ Warnings & Precautions

Warning: Accidental overdose of iron containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a physician or poison control center immediately.

🧪 Formulation Notes

Easy on the stomach Proven results Gentle Mild Effective

High potency iron Iron with essential nutrients for healthy red blood cells

Non GMO GF (Gluten free)

Unique synergistic nutritional support complex with over 25 years of proven results and millions of satisfied customers

Nutritional support for healthy blood Hema-Plex Softgels for those who prefer an easy-to-swallow softgel. Easy-to-swallow softgel

Enjoy high-potency, organically bound iron, with essential nutrients needed for optimal blood health. High-potency, naturally chelated iron with essential cofactors 3 softgels per serving deliver 85 mg elemental Iron

Free from synthetic: Colors, preservatives. Free from milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy and sesame.

Additional Information

Keep tightly closed in a cool, dry place.

For more information about Hema-Plex and the benefits and importance of iron, go to www.HemaPlex.com

Product Details

UPC / SKU 0 97467 37691 5
DSLD Entry Date 2024-10-24
Product Type Other Combinations
Form Softgel Capsule
Brand NaturesPlus
DSLD ID 319186
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
PubMed DOI Cochrane
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
PubMed DOI
View all evidence for Vitamin C →

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