Home/ Supplements/ Vitamin C/ Ultra-Stress Sustained Release

Ultra-Stress Sustained Release

product on market Tablet or Pill NaturesPlus Safety: 91/100
91/100

This product looks safe

  • Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
  • Vitamin B6: 125mg is 1.2× the Tolerable Upper Intake Level (100mg)
  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 69% of ingredients have research evidence
F Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins and vitamin C, which are supported by strong evidence for supporting energy metabolism and nervous system function. These nutrients play a key role in the body's physiological response to stress. The ingredient profile is associated with a high safety score of 91/100.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)

Vitamin B6: 125mg is 1.2× the Tolerable Upper Intake Level (100mg)

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Ultra-Stress Sustained Release
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
90
Servings
Other Combinations
Product Type
69%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
500 mg (556% DV)
125 mg (10417% DV)
104.2× RDA — above typical dose 76 studies (A:0, B:33)
125 mg (9615% DV)
96.2× RDA — above typical dose 13 studies (A:0, B:1)
125 mg NE (781% DV)
Exceeds UL by 3.6× (UL: 35 mg) 196 studies (A:5, B:63)
125 mg (7353% DV)
Exceeds UL by 1.2× (UL: 100 mg) 114 studies (A:3, B:35)
667 mcg DFE (167% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
500 mcg (20833% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
125 mcg (417% DV)
4.2× RDA — above typical dose 27 studies (A:0, B:11)
200 mg (4000% DV)
40.0× RDA — above typical dose 2 studies — no high-quality reviews
32 mg (6% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
Iron
20 mg (111% DV)
75 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews

Other Ingredients

Hydroxypropyl Methylcellulose Stearic Acid Microcrystalline Cellulose Ferrous Fumarate Magnesium Stearate Rose Hip Soy Protein Isolate Rice Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: One tablet daily, preferably with a meal.

Warnings & Precautions

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a physician or poison control center immediately.

Formulation Notes

Free from artificial colors and artificial preservatives. GF Gluten free

Vegetarian

In a special base which provides for the gradual release of ingredients over a prolonged period of time.

Micro-Gel Sustained Release System

B-Complex, Vitamin C & Iron

Stress Support

Additional Information

Keep tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU0 97467 01231 8
DSLD Entry Date2023-10-24
Product TypeOther Combinations
FormTablet or Pill
BrandNaturesPlus
DSLD ID298639
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.