3-in-1 Joint Formula

product on market Softgel Capsule Irwin Naturals 🟢 Safety: 97/100
Brand: Irwin Naturals
🟢 97/100

This product looks safe

  • Folate: 382mg is 382.0× the Tolerable Upper Intake Level (1.0mg)
  • Fish Oils: 3180mg is 1.1× the Tolerable Upper Intake Level (3000mg)
  • 46% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 382mg is 382.0× the Tolerable Upper Intake Level (1.0mg)
⚠️ Fish Oils: 3180mg is 1.1× the Tolerable Upper Intake Level (3000mg)

Label Data

6 Liquid Softgel(s) Serving Size
15 Servings
Other Combinations Product Type
46% Evidence Coverage

Supplement Facts — Evidence Check

Calories
60 Calorie(s)
Total Fat
3.5 Gram(s) (4% DV)
Cholesterol
15 mg (5% DV)
Total Carbohydrates
3 Gram(s) (1% DV)
Protein
3 Gram(s)
10 mg (67% DV)
✅ Within RDA (0.7× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 10mg UL 1000mg
23 mg (144% DV)
✅ 1.6× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 23mg UL 35mg
382 mcg DFE (96% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 382.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 382mg UL 1.0mg
120 mcg (5000% DV)
📊 50.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.12mg
7 mg (304% DV)
✅ 3.0× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 7mg UL 11mg
Sodium
95 mg (4% DV)
Potassium
250 mg (5% DV)
3180 mg
⚠️ Exceeds Tolerable Upper Intake Level by 1.1× (UL: 3000 mg) 📚 388 studies (Tier A: 18, B: 204)
This product: 3180mg UL 3000mg
1500 mg
📊 Market median: 1000.0mg (1115 products) 📚 22 studies (Tier A: 0, B: 9)
This product: 1500mg
1200 mg
📊 Market median: 600.0mg (79 products) 📚 24 studies (Tier A: 0, B: 6)
This product: 1200mg
150 mg
📊 Market median: 1000.0mg (212 products) 📚 12 studies (Tier A: 0, B: 3)
This product: 150mg
150 mg
📊 Market median: 1000.0mg (2 products)
This product: 150mg
115 mg
📊 Market median: 375.0mg (171 products) 📚 30 studies (Tier A: 1, B: 14)
This product: 115mg
Stinging Nettle leaf extract
70 mg
40 mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 40mg
5 mg
📊 Market median: 200.0mg (198 products) 📚 6 studies — no high-quality reviews
This product: 5mg
BioPerine Complex
6 mg

Other Ingredients

Gelatin Water, Purified Glycerin Soy Lecithin Annatto Maltodextrin Titanium Dioxide Dicalcium Phosphate Beeswax St. John's Bread Soybean Oil Turmeric

Label Claims — Verification

❓ Nutrient
❓ All Other
❓ Structure/Function
All Other (100% of products) Structure/Function (86% of products) Nutrient (18% of products)

Target Groups

Adult (18 - 50 Years) Women (not pregnant or lactating)

Product Information

📋 Directions for Use

Directions: (Adult) Take six (6) liquid soft-gels per day with a meal and a full glass (8 oz) of water. May be taken all at once or in divided doses.

⚠️ Warnings & Precautions

Usage warnings: Do not use if safety seal is broken.

Check with your doctor before using the product if you are using medication or have any medical conditions. Do not use if you may become pregnant, are pregnant or nursing.

Do not use if you have a bile duct obstruction. Do not exceed recommended daily intake.

Not intended for use by persons under 18. Keep out of reach or children.

Warning: (State of California Prop 65) This product contains a chemical known to the State of California to cause birth defects or other reproductive harm.

Contains: Crustacean Shellfish (crab, lobster, shrimp), Fish (anchovy, sardine), Soy

🧪 Formulation Notes

3-in-1 Joint Formula combines nutrients, oils and botanical extracts to promote joint comfort. This powerful formula is designed to support healthy joints in three distinct ways: Rebuild: The well-known ingredients of Glucosamine and Chondroitin are included in this formula to help rebuild cartilage. These nutrients promote healthy tissues and help to maintain joint structure and mobility. Lubricate: Glucosamine and Chondroitin enhance the lubricating synovial fluid that cushions and supports joints. These nutrients support joint comfort. Soothes: This formula is enhanced by the inclusion of Omega-3 Fatty Acids from Fish Oil and Flaxseed Oil. It also delivers a blend of soothing botanical extracts, including Boswellia, Turmeric and Stinging Nettle.

3-in-1 Joint Formula can help to rebuild, lubricate and soothe your joints. This advanced combination of nutrients can give you the support you need to promote long-term joint and connective tissue health. What makes us different: Liquid Soft-gels - The nutrients in these easy-to-swallow liquid soft-gels are released fast. Other forms of delivery can contain binders and fillers that may cause stomach upset and offer no nutritional value. Advanced Liquid Soft-Gels provide an optimum delivery system.

Quality Assurance - Irwin Naturals is committed to providing the highest quality products for your health. We employ compliance testing to ensure purity and potency.

Patented BioPerine - Our special BioPerine Complex enhances the bioavailability, absorption and potency of many nutrients.

Glucosamine Chondroitin MSM Omega 3 Turmeric

(1) Rebuild (2) Lubricate (3) Soothe

No preservatives added.

Additional Information

Pass Quality Tested Guaranteed

Global responsibility - Over the years we have donated to organizations that support the environment and the health of our children.

Store in a cool, dry place.

Questions: Contact Consumer Affairs 1-800-297-3273 - Weekdays 8:00 am to 5:00 pm (PST) 100+ Highly Specialized Products: www.IrwinNaturals.com

Full disclosure ingredient panel

Product Details

UPC / SKU 7 10363 26242 6
DSLD Entry Date 2023-06-22
Product Type Other Combinations
Form Softgel Capsule
Brand Irwin Naturals
DSLD ID 292060
Data Updated 2026-04-11

Research Evidence

2 Research Sources
42 Avg Quality Score
2 Rct
C Pharmacokinetic assessment of constituents of Boswellia serrata, pine bark extracts, curcumin in combination including methylsulfonylmethane in healthy volunteers.
Rct The Journal of pharmacy and pharmacology
PubMed DOI
C [Comparative efficacy of a combination of undenatured type II collagen, Boswellic acids, methylsulfonylmethane, vitamins C and D3 and a combination of chondroitin sulfate and glucosamine hydrochloride in the treatment of primary osteoarthritis of the knee joint].
Rct Terapevticheskii arkhiv
PubMed DOI
View all evidence for Msm →

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