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Stress B Complex with C-500

product on market Other (e.g. tea bag) Puritan's Pride Safety: 85/100
85/100

This product is generally safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 71% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines B vitamins and Vitamin C, which have strong evidence for supporting energy metabolism and immune function. Research indicates these nutrients play essential roles in cellular health and stress response. The overall evidence coverage for this specific combination is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for Stress B Complex with C-500
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Caplet(s)
Serving Size
Other Combinations
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
500 mg (556% DV)
50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (3846% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
100 mg (625% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2941% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
666 mcg DFE (167% DV)
Exceeds UL by 666.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
1000 mcg (41667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
10 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
10 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Proprietary Blend
5 mg

Other Ingredients

Cellulose Stearic Acid Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Info

Product Information

Directions for Use

Directions: For adults, take one (1) caplet daily, preferably with a meal.

Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medication, or are planning to undergo any clinical lab testing, consult your doctor before use. Some supplements may interact with certain medications and/or interfere with certain lab tests.

If any adverse reactions occur, stop use and consult your doctor.

Avoid this product if you are allergic to yeast.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Contains wheat and soy ingredients. Contains bioengineered food ingredients.

Formulation Notes

Timed release

Vegetarian Vitamin Supplement

Additional Information

Store at room temperature.

To reorder item #334 www.puritan.com 1-800-645-1030

QA Quality Assured

Metadata

Product Details

UPC / SKU0 74312 10334 6
DSLD Entry Date2023-05-24
Product TypeOther Combinations
FormOther (e.g. tea bag)
BrandPuritan's Pride
DSLD ID285659
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.