Stress B Complex with C-500

product on market Other (e.g. tea bag) Puritan's Pride 🟢 Safety: 85/100
Brand: Puritan's Pride
🟢 85/100

This product is generally safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 71% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

1 Caplet(s) Serving Size
Other Combinations Product Type
71% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C
500 mg (556% DV)
50 mg (4167% DV)
📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 50mg
50 mg (3846% DV)
📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 50mg
100 mg (625% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 100mg UL 35mg
50 mg (2941% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
666 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 666.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 666mg UL 1.0mg
1000 mcg (41667% DV)
📊 416.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 1.0mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
50 mg (1000% DV)
📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 50mg
10 mg
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 10mg UL 3500mg
10 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 10mg
10 mg
📊 Market median: 500.0mg (9 products)
This product: 10mg
10 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 10mg
Proprietary Blend
5 mg

Other Ingredients

Cellulose Stearic Acid Silica Magnesium Stearate

Label Claims — Verification

❓ Nutrient
❓ All Other
All Other (99% of products) Structure/Function (83% of products) Nutrient (54% of products)

Target Groups

Vegetarian Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: For adults, take one (1) caplet daily, preferably with a meal.

⚠️ Warnings & Precautions

Warning: If you are pregnant, nursing, taking any medication, or are planning to undergo any clinical lab testing, consult your doctor before use. Some supplements may interact with certain medications and/or interfere with certain lab tests.

If any adverse reactions occur, stop use and consult your doctor.

Avoid this product if you are allergic to yeast.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Contains wheat and soy ingredients. Contains bioengineered food ingredients.

🧪 Formulation Notes

Timed release

Vegetarian Vitamin Supplement

Additional Information

Store at room temperature.

To reorder item #334 www.puritan.com 1-800-645-1030

QA Quality Assured

Product Details

UPC / SKU 0 74312 10334 6
DSLD Entry Date 2023-05-24
Product Type Other Combinations
Form Other (e.g. tea bag)
Brand Puritan's Pride
DSLD ID 285659
Data Updated 2026-04-11

Research Evidence

371 Research Sources
54 Avg Quality Score
148 Meta Analysis
82 Systematic Review
71 Rct
62 Clinical Trial
2 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Other
1 Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI Cochrane
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017
PubMed DOI Cochrane
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015
PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020
PubMed DOI Cochrane
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021
PubMed DOI Cochrane
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024
PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024
PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021
PubMed DOI
View all evidence for Vitamin C →

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