100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 56% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6
· methodology
This formula contains minerals and nutrients like magnesium, calcium, and selenium, which support cardiovascular and metabolic functions. Research provides strong evidence for the roles of these minerals in heart health and cellular protection. However, the overall evidence coverage for this specific ingredient combination is limited.
AI-generated summary based on research evidence. Not medical advice.
Details
Label Data
3 Capsule(s)
Serving Size
Other Combinations
Product Type
Ingredients
Supplement Facts — Evidence Check
Within RDA (0.2× RDA)
38 studies (A:1, B:7)
Within RDA (0.7× RDA)
316 studies (A:8, B:159)
1.3× RDA — within safe limits
173 studies (A:0, B:67)
ChromeMate CM-100
200 mcg
(571% DV)
Market median: 500.0mg (180 products)
5 studies (A:0, B:1)
Market median: 333.0mg (166 products)
9 studies (A:0, B:2)
Market median: 500.0mg (861 products)
61 studies (A:4, B:13)
Market median: 600.0mg (79 products)
25 studies (A:0, B:6)
Market median: 100.0mg (283 products)
144 studies (A:1, B:64)
Market median: 200.0mg (136 products)
3 studies — no high-quality reviews
Market median: 550.0mg (217 products)
29 studies (A:0, B:5)
Market median: 500.0mg (193 products)
7 studies — no high-quality reviews
Market median: 500.0mg (223 products)
24 studies (A:0, B:1)
Other Ingredients
Gelatin
Water, Purified
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
Recommendations: Take three (3) to six (6) capsules daily, or as directed by your physician.
Warnings & Precautions
Warning: If you are pregnant or breast feeding, consult your physician before using this product. May cause a reaction with thyroid medications.
If heart palpitations occur, discontinue use.
Do not exceed six (6) capsules in a 24 hour period.
Keep out of reach of children.
Formulation Notes
Contains no preservatives.
Cardio Plus
(With CoenzymeQ10)
Non-GMO
Additional Information
Keep container tightly closed, store in a cool, dry place.
Bisphenol-A (BPA) & Phthalate Free
GMP Certified
For professional use only.
Metadata
Product Details
UPC / SKU8 15354 02034 1
DSLD Entry Date2023-02-21
Product TypeOther Combinations
FormCapsule
Data Updated2026-04-11
Research
Research Evidence
B
Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis
Biological psychiatry. Cognitive neuroscience and neuroimaging
2024
PubMed
DOI
B
Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline
Briefings in bioinformatics
2026
PubMed
DOI
B
Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline
Journal of gastroenterology
2022
PubMed
DOI
B
Scientific Opinion on health claims related to choline
Regulatory Source
EFSA Journal
2011
DOI
C
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis
Nutrition reviews
2022
PubMed
DOI
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review
Psychotherapy and psychosomatics
2013
PubMed
DOI
C
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct
The British journal of nutrition
2007
PubMed
C
Differential metabolism of choline supplements in adult volunteers.
View all evidence for Choline →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.