🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 100% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Label Data

1 Capsule(s) Serving Size
Single Vitamin and Mineral Product Type
100% Evidence Coverage

Supplement Facts — Evidence Check

100 mg (18% DV)
✅ Within RDA (0.2× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 100mg UL 3500mg
5 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 5mg

Other Ingredients

Microcrystalline Cellulose purified Water Capsule Shell

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take one capsule, two times per day.

⚠️ Warnings & Precautions

Consult your healthcare professional prior to use if you have or suspect a medical condition, are taking prescription drugs, or are pregnant or lactating.

Keep out of the reach of children.

🧪 Formulation Notes

This product does not contain soy, dairy, egg, corn, wheat, gluten, fish/shellfish, nuts/tree nuts.

V Vegan Vegetarian

ch-OSA Advanced collagen generator

ch-OSA Original Formula

Additional Information

Store at 59-86(0)F (15-30(0)C). Protect from light and moisture.

V Vegan Vegetarian

isura Non-GMO - Mass spec Documentation - Lab tested

Reduces fine lines and wrinkles Thickens and strengthens hair Strengthens nails Promotes healthy bones and joints

Clinically proven

Made in Belgium

The breakthrough in collagen! Collagen is essential for beautiful skin, hair and nails as well as healthy bones and joints. But starting at age 21, collagen diminishes 1% per year. By age 30, the signs become visible. For years, scientists searched for a method to give the human body the ability to regenerate its own collagen.

Nourish your body's 3 "beauty proteins" - naturally! The condition of your skin, hair, and nails depends on three proteins: Collagen "plumps out" skin, removing wrinkles and preventing them form forming. In addition, collagen is essential for strong, healthy bones and joints. Keratin is the protein that's packed into your hair shaft. It gives your hair thickness, body, strength, and elasticity. Plus, keratin gives your nails strength. Elastin gives your skin its ability to stretch and "bounce back" preventing fine lines and wrinkles. With age, collagen, keratin and elastin decline.

Strengthens hair First 36 weeks Break load (N) .58 .60 .65 .70 .73 Placebo 0.61 ch-OSA (2 caps/day) 0.69 13.1% stronger hair with ch-OSA

Reduces depth of wrinkles First 20 weeks Change in wrinkle depth -20% -15% -10% -5% 0 +5% +10% +15% +20% Placebo -11% ch-OSA (2 caps/day) 30% net improvement in wrinkle depth with ch-OSA

Product Details

UPC / SKU 5 425010 39182 8
DSLD Entry Date 2017-08-22
Product Type Single Vitamin and Mineral
Form Capsule
Brand BioSil
DSLD ID 77061
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

Compare Similar Products

View all Choline products →