100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 100% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6 · grounded in 1 source
· methodology
Choline supports cognitive function and liver health, while silicon is associated with the maintenance of connective tissues and bone density. Research evidence for these specific applications is generally moderate. The ingredient profile maintains a high safety rating.
AI-generated summary based on research evidence. Not medical advice.
Details
Label Data
1 Capsule(s)
Serving Size
Single Vitamin and Mineral
Product Type
Ingredients
Supplement Facts — Evidence Check
Within RDA (0.2× RDA)
38 studies (A:1, B:7)
Market median: 108.0mg (8 products)
9 studies (A:0, B:4)
Other Ingredients
Microcrystalline Cellulose
HPMC
purified Water
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
DIRECTIONS: Take one capsule two times per day, or as directed by your healthcare practitioner.
Warnings & Precautions
CAUTIONS: Consult your healthcare practitioner before use, especially if you have or suspect you have a medical condition, are taking prescription drugs, or are pregnant or lactating.
Keep out of reach of children.
Avoid if allergic to any ingredient.
Formulation Notes
DOES NOT CONTAIN: Wheat, gluten, corn, yeast, soy, animal or dairy products, fish, shellfish, peanuts, tree nuts, egg, artificial colors, artificial sweeteners, or preservatives.
Additional Information
STORAGE: Store in a cool, dry place.
EXCLUSIVE PATENTED
ISSUED U.S. PATENT
Advanced Collagen Generator
PHARMACEUTICAL GRADE
PROFESSIONAL USE ONLY
MADE IN BELGIUM
Vegetable CAPSULES
REV. 040412
Metadata
Product Details
DSLD Entry Date2013-12-24
Product TypeSingle Vitamin and Mineral
FormCapsule
Data Updated2026-04-11
Research
Research Evidence
B
Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis
Biological psychiatry. Cognitive neuroscience and neuroimaging
2024
PubMed
DOI
B
Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline
Briefings in bioinformatics
2026
PubMed
DOI
B
Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline
Journal of gastroenterology
2022
PubMed
DOI
B
Scientific Opinion on health claims related to choline
Regulatory Source
EFSA Journal
2011
DOI
C
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis
Nutrition reviews
2022
PubMed
DOI
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review
Psychotherapy and psychosomatics
2013
PubMed
DOI
C
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct
The British journal of nutrition
2007
PubMed
C
Differential metabolism of choline supplements in adult volunteers.
View all evidence for Choline →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.
