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Activated B-Complex High Bioavailability

product on market Capsule Swanson Safety: 93/100
93/100

This product looks safe

  • Niacinamide: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
  • 82% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This blend of B vitamins, including folate and B12, supports energy metabolism and neurological function. There is strong clinical evidence for the role of these nutrients in cellular health and red blood cell formation. The profile maintains a high safety score, indicating a low risk of adverse effects for most users.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacinamide: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Activated B-Complex High Bioavailability
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Veggie Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
82%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

25 mg (1923% DV)
19.2× RDA — above typical dose 13 studies (A:0, B:1)
50 mg NE (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
25 mg (1471% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg DFE (100% DV)
Exceeds UL by 400.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
250 mcg (10417% DV)
104.2× RDA — above typical dose 139 studies (A:1, B:44)
25 mcg (83% DV)
Within RDA (0.8× RDA) 27 studies (A:0, B:11)
25 mg (5% DV)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
36 mg
30.0× RDA — above typical dose 76 studies (A:0, B:33)
25 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
Pantethine
25 mg
12.5 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)

Other Ingredients

Microcrystalline Cellulose Cellulose Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, take one veggie capsule one to two times per day with water.

Warnings & Precautions

Warning: For adults only.

Consult your healthcare provider before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Keep out of reach of children.

Do not use if seal is broken.

Formulation Notes

Promotes nervous system, immune and cardiovascular health Supports neurotransmitter production for a positive mood

Energy and Metabolism High Bioavailability

Additional Information

swanson.com or call 1-800-437-4148

Science-Backed Quality since 1969

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 87614 02815 6
DSLD Entry Date2022-06-16
Product TypeOther Combinations
FormCapsule
BrandSwanson
DSLD ID264944
Data Updated2026-04-11
Research

Research Evidence

22
Research Sources
49
Avg Quality
8
Rct
4
Meta Analysis
4
Clinical Trial
3
Systematic Review
1
Cochrane Review
1
Regulatory Source
B Effect of vitamin B2, vitamin C, vitamin D, vitamin E and folic acid in adults with essential hypertension: a systematic review and network meta-analysis
Systematic Review BMJ open 2024 PubMed DOI
B Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2022 PubMed DOI
B Supplementary vitamin E, selenium, cysteine and riboflavin for preventing kwashiorkor in preschool children in developing countries
Systematic Review The Cochrane database of systematic reviews 2010 PubMed DOI
B Riboflavin supplements for blood pressure lowering in adults.
Cochrane Review The Cochrane database of systematic reviews PubMed DOI
B Associations of dietary vitamin B1, vitamin B2, vitamin B6, and vitamin B12 with the risk of depression: a systematic review and meta-analysis
Meta Analysis Nutrition reviews 2022 PubMed DOI
C Prophylaxis of migraine headaches with riboflavin: A systematic review
Systematic Review Journal of clinical pharmacy and therapeutics 2017 PubMed DOI
C Medium-dose riboflavin as a prophylactic agent in children with migraine: a preliminary placebo-controlled, randomised, double-blind, cross-over trial
Rct Cephalalgia : an international journal of headache 2010 PubMed DOI
C The efficacy of 2 different phakic intraocular lens implant in keratoconus as an isolated procedure or combined with collagen crosslinking and intra-stromal corneal ring segments: a systematic review and meta-analysis
Meta Analysis International ophthalmology 2023 PubMed DOI
C Epithelium-off photochemical corneal collagen cross-linkage using riboflavin and ultraviolet a for keratoconus and keratectasia: a systematic review and meta-analysis
Meta Analysis The ocular surface 2014 PubMed DOI
C Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial
Rct The journal of headache and pain 2015 PubMed DOI
View all evidence for Riboflavin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.