Stress B with Zinc by 21st Century — Ingredients, Evidence & Safety

🟢 94/100

This product looks safe

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
77% of ingredients have research evidence

D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

66 Servings

Multi-Vitamin and Mineral (MVM) Product Type

77% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin C

500 mg (556% DV)

Vitamin E

13.5 mg (90% DV)

✅ Within RDA (0.9× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 13.5mg UL 1000mg

Thiamine

10 mg (833% DV)

📊 8.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 10mg

Riboflavin

10 mg (769% DV)

📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 10mg

Niacin

100 mg (625% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 2.9× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 100mg UL 35mg

Vitamin B6

5 mg (294% DV)

📊 3.8× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 5mg UL 100mg

Folate

667 mcg DFE (167% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 667mg UL 1.0mg

Vitamin B12

12 mcg (500% DV)

📊 5.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.012mg

Biotin

45 mcg (150% DV)

✅ 1.5× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.045mg

Pantothenic Acid

20 mg (400% DV)

📊 4.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 20mg

Calcium

70 mg (5% DV)

Zinc

23.9 mg (217% DV)

✅ 2.2× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 23.9mg UL 40mg

Copper

3 mg (333% DV)

📊 3.3× RDA — above typical dose (UL: 10 mg) 📚 36 studies (Tier A: 0, B: 11)

RDA 0.9mg This product: 3mg UL 10mg

Other Ingredients

Starch Cellulose Hydroxypropyl Methylcellulose Contains Less Than 2% of

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (84% of products) Nutrient (48% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Directions: As a vitamin supplement, adults take one (1) tablet daily with any meal or as directed by a healthcare provider. Do not exceed recommended dosage.

⚠️ Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

🧪 Formulation Notes

No added yeast or preservatives.

Energy & immune support

Gluten free

Additional Information

Individual results may vary.

Store at room temperature.

Periods of stress can be taxing on the body. Combined with a healthy diet and plenty of rest, 21st Century Stress B helps provide the extra nutritional support your body may need.

Guaranteed quality Laboratory tested

Product Details

UPC / SKU 7 40985 22331 4

DSLD Entry Date 2022-01-22

Product Type Multi-Vitamin and Mineral (MVM)

Form Tablet or Pill

Brand 21st Century

DSLD ID 258595

Data Updated 2026-04-11

Research Evidence

397 Research Sources

55 Avg Quality Score

200 Meta Analysis

68 Rct

58 Systematic Review

53 Clinical Trial

9 Cochrane Review

2 Narrative Review

2 Regulatory Source

1 Observational

1 Other

1 Openfda Safety

A Zinc supplementation for improving pregnancy and infant outcome

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI Cochrane

A Zinc supplementation for preventing mortality, morbidity, and growth failure in children aged 6 months to 12 years

Narrative Review The Cochrane database of systematic reviews 2023

PubMed DOI Cochrane

A Oral zinc for treating diarrhoea in children

Meta Analysis The Cochrane database of systematic reviews 2016

PubMed DOI

A Zinc supplements for preventing otitis media

Meta Analysis The Cochrane database of systematic reviews 2014

PubMed DOI Cochrane

A Zinc for the prevention or treatment of acute viral respiratory tract infections in adults: a rapid systematic review and meta-analysis of randomised controlled trials

Meta Analysis BMJ open 2021

PubMed DOI

A Zinc supplements for preventing otitis media

Meta Analysis The Cochrane database of systematic reviews 2010

PubMed DOI Cochrane

A Zinc supplements for preventing otitis media

Meta Analysis The Cochrane database of systematic reviews 2012

PubMed DOI Cochrane

A Compression bandages or stockings versus no compression for treating venous leg ulcers

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

A Zinc supplementation for mental and motor development in children