B-Complex + 10 mg 5-MTHF
93/100
This product looks safe
- Niacin: 150mg is 4.3× the Tolerable Upper Intake Level (35mg)
- Folate: 10mg is 10.0× the Tolerable Upper Intake Level (1.0mg)
- 82% of ingredients have research evidence
D
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 150mg is 4.3× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 10mg is 10.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 Capsule(s)
Serving Size
Other Combinations
Product Type
82%
Evidence Coverage
Supplement Facts — Evidence Check
25 mg
(1667% DV)
📊 20.8× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
25 mg
(1471% DV)
📊 19.2× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
150 mg
(750% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 4.3× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
55 mg
(2750% DV)
📊 42.3× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
10 mg
(2500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 10.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
1000 mcg
(16667% DV)
📊 416.7× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
400 mcg
(133% DV)
📊 13.3× RDA — above typical dose
📚 26 studies (Tier A: 0, B: 11)
150 mg
(1500% DV)
📊 30.0× RDA — above typical dose
📚 1 studies — no high-quality reviews
50 mg
✅ Within RDA (0.1× RDA of 550 mg)
📚 36 studies (Tier A: 1, B: 7)
50 mg
📊 Market median: 550.0mg (217 products)
📚 29 studies (Tier A: 0, B: 5)
50 mg
📊 Market median: 500.0mg (9 products)
Other Ingredients
vegetarian capsule
L-Leucine
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (77% of products)
Nutrient (60% of products)
Approved Health (5% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
DIRECTIONS: Use only as directed by a healthcare professional.
⚠️ Warnings & Precautions
Keep tightly closed in a cool, dry place out of the reach of children.
CAUTION: Consult your healthcare professional before taking this product.
🧪 Formulation Notes
High-potency B-Complex with phosphorylated B-2 and B-6, methylated B-12, PLUS 10 mg 5-MTHF.
Gluten and Excipient-free
Additional Information
Keep tightly closed in a cool, dry place out of the reach of children.
Manufactured in a GMP Compliant Facility
535001A EXP 5/14
ESSENTIALS
V.01
Product Details
UPC / SKU
8 38287 00535 3
DSLD Entry Date
2013-08-23
Product Type
Other Combinations
Form
Capsule
Brand
Metabolic Maintenance
DSLD ID
24746
Data Updated
2026-04-11
Research Evidence
363
Research Sources
57
Avg Quality Score
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A
Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
A
Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
A
The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
A
A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A
Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
A
Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
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