Milk Thistle by Fresh Nutrition — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
87% of ingredients have research evidence

A Label Compliance Grade

Product Label

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Label Data

2 Softgel Capsule(s) Serving Size

30 Servings

Other Combinations Product Type

87% Evidence Coverage

Supplement Facts — Evidence Check

Milk Thistle

95 mg

📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)

This product: 95mg

Vitamin A Palmitate

1 mg

✅ 1.1× RDA — within safe limits 📚 240 studies (Tier A: 5, B: 97)

RDA 0.9mg This product: 1mg UL 3.0mg

Vitamin E

11 mg

✅ Within RDA (0.7× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)

RDA 15mg This product: 11mg UL 1000mg

Nicotinamide

10 mg

✅ Within RDA (0.7× RDA of 14 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 10mg UL 35mg

Vitamin B2

1000 mcg

✅ Within RDA (0.8× RDA of 1.3 mg) 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 1.0mg

Vitamin B6

500 mcg

✅ Within RDA (0.4× RDA of 1.3 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 0.5mg UL 100mg

Folic Acid

60 mcg

✅ Within RDA (0.1× RDA of 0.4 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.06mg UL 1.0mg

Vitamin B12

1 mcg

✅ Within RDA (0.4× RDA of 0.0024 mg) 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.001mg

Vitamin B1

1000 mcg

✅ Within RDA (0.8× RDA of 1.2 mg) 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 1.0mg

Pantothenic Acid

2170 mcg

✅ Within RDA (0.4× RDA of 5 mg) 📚 1 studies — no high-quality reviews

RDA 5mg This product: 2.17mg

Biotin

3 mcg

✅ Within RDA (0.1× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.003mg

Vitamin C

10 mg

Inositol

10 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 10mg

Choline Bitartrate

10 mg

📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 10mg UL 3500mg

Zinc

9 mg

✅ Within RDA (0.8× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 9mg UL 40mg

Other Ingredients

Vegetarian Capsules organic Rice extract

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (4% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommended Dosage Take two (2) softgel capsules daily with sufficient water before a meal.

🧪 Formulation Notes

Vegan

Non GMO Gluten free Soy free

Milk Thistle Milk Thistle contains Silymarin, a group of naturally occurring full spectrum flavon lignan, which is well known for its liver support. We combat numerous free radicals on a daily basis that by supplementing with organic milk thistle, promotes the liver's natural detoxification process.

No artificial colors. No artificial flavors. No preservatives. Made with Non-GMO, all natural ingredients!

Made with Non-GMO, all natural ingredients!

Made with organic Milk Thistle 500 mg of Organic Milk Thistle

Natural detox May assist healthy liver function

Fresh Nutrition produces the most potent and highest quality Milk Thistle. Our raw materials are carefully sourced and cultivated; contain no fillers, additives, and are manufactured domestically in a cGMP facility. Thank you for choosing Fresh!

Additional Information

Fresh Nutrition Our goal is to create high-quality natural products using both organic and responsibly sourced ingredients to optimize health and well-being.

Quality Verified Third Party Tested For Quality And Purity To provide our consumers with complete confidence in our product quality, every batch is 3rd party tested for quality & purity.

Made in USA

Product Details

UPC / SKU 8 50012 95650 1

DSLD Entry Date 2021-02-25

Product Type Other Combinations

Form Softgel Capsule

Brand Fresh Nutrition

DSLD ID 242022

Data Updated 2026-04-11

Research Evidence

69 Research Sources

55 Avg Quality Score

34 Meta Analysis

26 Systematic Review

5 Rct

3 Clinical Trial

1 Openfda Safety

A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease

Meta Analysis The Cochrane database of systematic reviews 2025

PubMed DOI Cochrane

B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis

Meta Analysis Japan journal of nursing science : JJNS 2024

PubMed DOI

B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications

Meta Analysis Asia Pacific journal of clinical nutrition 2025

PubMed DOI

B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases

Meta Analysis The Cochrane database of systematic reviews 2007

PubMed

B Pharmacotherapy for trichotillomania

Meta Analysis The Cochrane database of systematic reviews 2021

PubMed DOI

B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition ESPEN 2022

PubMed DOI

B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review

Meta Analysis Medicine 2024

PubMed DOI

B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury

Meta Analysis BMC complementary medicine and therapies 2025

PubMed DOI

B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis

Meta Analysis Medicine 2020

PubMed DOI

B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis

Meta Analysis Annals of hepatology 2024

PubMed DOI

View all evidence for Milk Thistle →