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Milk Thistle

product on market Softgel Capsule Fresh Nutrition Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 87% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Milk thistle is researched for its potential to support liver function, though evidence is often considered limited or mixed. The accompanying B vitamins and antioxidants like Vitamin E and A support general cellular health and metabolic processes. Research for these combined ingredients is well-established, though the overall evidence coverage for this specific formulation is low.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Milk Thistle
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Softgel Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
87%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

95 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
1.1× RDA — within safe limits 241 studies (A:5, B:97)
11 mg
Within RDA (0.7× RDA) 179 studies (A:3, B:90)
10 mg
Within RDA (0.7× RDA) 196 studies (A:5, B:63)
1000 mcg
Within RDA (0.8× RDA) 13 studies (A:0, B:1)
500 mcg
Within RDA (0.4× RDA) 114 studies (A:3, B:35)
60 mcg
Within RDA (0.1× RDA) 226 studies (A:10, B:105)
1 mcg
Within RDA (0.4× RDA) 139 studies (A:1, B:44)
1000 mcg
Within RDA (0.8× RDA) 76 studies (A:0, B:33)
2170 mcg
Within RDA (0.4× RDA) 2 studies — no high-quality reviews
3 mcg
Within RDA (0.1× RDA) 27 studies (A:0, B:11)
Vitamin C
10 mg
10 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
9 mg
Within RDA (0.8× RDA) 263 studies (A:6, B:134)

Other Ingredients

Vegetarian Capsules organic Rice extract
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Recommended Dosage Take two (2) softgel capsules daily with sufficient water before a meal.

Formulation Notes

Vegan

Non GMO Gluten free Soy free

Milk Thistle Milk Thistle contains Silymarin, a group of naturally occurring full spectrum flavon lignan, which is well known for its liver support. We combat numerous free radicals on a daily basis that by supplementing with organic milk thistle, promotes the liver's natural detoxification process.

No artificial colors. No artificial flavors. No preservatives. Made with Non-GMO, all natural ingredients!

Made with Non-GMO, all natural ingredients!

Made with organic Milk Thistle 500 mg of Organic Milk Thistle

Natural detox May assist healthy liver function

Fresh Nutrition produces the most potent and highest quality Milk Thistle. Our raw materials are carefully sourced and cultivated; contain no fillers, additives, and are manufactured domestically in a cGMP facility. Thank you for choosing Fresh!

Additional Information

Fresh Nutrition Our goal is to create high-quality natural products using both organic and responsibly sourced ingredients to optimize health and well-being.

Quality Verified Third Party Tested For Quality And Purity To provide our consumers with complete confidence in our product quality, every batch is 3rd party tested for quality & purity.

Made in USA

Metadata

Product Details

UPC / SKU8 50012 95650 1
DSLD Entry Date2021-02-25
Product TypeOther Combinations
FormSoftgel Capsule
DSLD ID242022
Data Updated2026-04-11
Research

Research Evidence

69
Research Sources
55
Avg Quality
34
Meta Analysis
26
Systematic Review
5
Rct
3
Clinical Trial
1
Openfda Safety
A Silymarin for adults with metabolic dysfunction-associated steatotic liver disease
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
B Evaluation of the effect of herbal agents as management of radiodermatitis in breast cancer patients: A systematic review and meta-analysis
Meta Analysis Japan journal of nursing science : JJNS 2024 PubMed DOI
B Efficacy of different interventions for nonalcoholic fatty liver disease: A meta-analysis of lifestyle modifications, silymarin, and medications
Meta Analysis Asia Pacific journal of clinical nutrition 2025 PubMed DOI
B Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases
Meta Analysis The Cochrane database of systematic reviews 2007 PubMed
B Pharmacotherapy for trichotillomania
Meta Analysis The Cochrane database of systematic reviews 2021 PubMed DOI
B Effects berberine-silymarin on liver enzymes: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition ESPEN 2022 PubMed DOI
B Efficacy of traditional Chinese medicine combined with Silibinin on nonalcoholic fatty liver disease: A meta-analysis and systematic review
Meta Analysis Medicine 2024 PubMed DOI
B Are alterations needed in Silybum marianum (Silymarin) administration practices? A novel outlook and meta-analysis on randomized trials targeting liver injury
Meta Analysis BMC complementary medicine and therapies 2025 PubMed DOI
B The therapeutic effects of silymarin for patients with glucose/lipid metabolic dysfunction: A meta-analysis
Meta Analysis Medicine 2020 PubMed DOI
B Administration of silymarin in NAFLD/NASH: A systematic review and meta-analysis
Meta Analysis Annals of hepatology 2024 PubMed DOI
View all evidence for Milk Thistle →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.