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PrePLUS Tablet

product on market Tablet or Pill Virtus Pharmaceuticals Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 71% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The product contains a blend of essential vitamins, including A, C, D, E, and thiamine, which support immune function and cellular health. There is strong research evidence supporting the role of these nutrients in maintaining general physiological wellness. The ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for PrePLUS Tablet
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
Multi-Vitamin and Mineral (MVM)
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
4000 IU (50% DV)
Vitamin C
120 mg (200% DV)
400 IU (100% DV)
Within RDA (0.7× RDA) 608 studies (A:16, B:251)
22 IU (73% DV)
Within RDA (1.0× RDA) 179 studies (A:3, B:90)
1.84 mg (108% DV)
1.5× RDA — within safe limits 76 studies (A:0, B:33)
3 mg (150% DV)
2.3× RDA — within safe limits 13 studies (A:0, B:1)
20 mg (100% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
10 mg (400% DV)
7.7× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1 mg (125% DV)
2.5× RDA — within safe limits 226 studies (A:10, B:105)
12 mcg (150% DV)
5.0× RDA — above typical dose 139 studies (A:1, B:44)
Calcium
200 mg (15% DV)
Iron
27 mg (150% DV)
25 mg (167% DV)
2.3× RDA — within safe limits 263 studies (A:6, B:134)
2 mg (100% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Silicon Dioxide FD&C Red #40 (Lakes) FD&C Blue #2 Aluminum Lake FD&C Yellow Lake #5
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Dosage and administration: Before, during and/or after pregnancy, one tablet daily, with a meal, or as directed by a licensed healthcare practitioner regardless of lactation status.

Warnings & Precautions

Contains FD&C Red #40 (Lakes), FD&C Blue #2 Aluminum Lake, and FD&C Yellow Lake #5.

Description: PrePLUS (PNV-Ca with 27 mg Fe; 1 mg FA) Tablet is an orally administered prenatal/postnatal prescription folic acid-containing dietary supplement and should be administered under the supervision of a licensed medical practitioner.

Warning: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

Caution: High levels of folic acid may, especially in older adults, hide signs of Vitamin B-12 deficiency (such as pernicious anemia), a condition that can cause nerve damage.

Call your licensed medical practitioner about side effects. You may report side effects by calling Virtus at 1-888-848-3593 or 1-800-FDA-1088.

Formulation Notes

(PNV-Ca with 27 mg Fe; 1 mg FA)

Prescription Folic Acid-Containing Dietary Supplement

Contains FD&C Red #40 (Lakes), FD&C Blue #2 Aluminum Lake, and FD&C Yellow Lake #5.

Additional Information

69543-258-50

Rx Made in USA

Store at 15(0) - 30 (0)C (59(0) - 86(0)F). [See USP Controlled Room Temperature.] Protect from light and moisture. Dispense in a tight, light-resistant container. Notice: Contact with moisture may produce surface discoloration or erosion.

How supplied: Supplied as beige tablet, imprinted "V258 dispensed in bottles of 500 tablets.

Rev. 03/15

Metadata

Product Details

UPC / SKU3 69543 25850 8
DSLD Entry Date2018-09-21
Product TypeMulti-Vitamin and Mineral (MVM)
FormTablet or Pill
BrandVirtus Pharmaceuticals
DSLD ID180495
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.