Is 1000 IU of Vitamin D3 safe?

Yes — this is 1.7× the recommended daily intake of 0.015 mg, which is within safe limits.

Multi Adult Gummies by Nature Made — Ingredients, Evidence & Safety

🟢 100/100

This product looks safe

No ingredients exceed tolerable upper intake levels
60% of ingredients have research evidence

A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This product contains vitamins A, C, and D3, which are supported by strong evidence for maintaining immune function and bone health. However, the overall evidence coverage for this specific ingredient profile is very low at 0.6%. The formulation maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Product Label

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Label Data

2 Gummie(s) Serving Size

15 Servings

Multi-Vitamin and Mineral (MVM) Product Type

60% Evidence Coverage

Supplement Facts — Evidence Check

Calories

15 Calorie(s)

Total Carbohydrates

4 Gram(s) (1% DV)

Vitamin A

2500 IU (50% DV)

Vitamin C

60 mg (100% DV)

Vitamin D3

1000 IU (250% DV)

✅ 1.7× RDA — within safe limits 📚 608 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.025mg UL 0.1mg

Vitamin E

30 IU (100% DV)

✅ 1.3× RDA — within safe limits 📚 179 studies (Tier A: 3, B: 90)

RDA 15mg This product: 20.1mg UL 1000mg

Niacin

20 mg (100% DV)

✅ 1.4× RDA — within safe limits 📚 196 studies (Tier A: 5, B: 63)

RDA 14mg This product: 20mg UL 35mg

Vitamin B6

2 mg (100% DV)

✅ 1.5× RDA — within safe limits 📚 114 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 2mg UL 100mg

Folic Acid

400 mcg (100% DV)

✅ Within RDA (1.0× RDA of 0.4 mg) 📚 226 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 0.4mg UL 1.0mg

Vitamin B12

6 mcg (100% DV)

✅ 2.5× RDA — within safe limits 📚 139 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.006mg

Biotin

150 mcg (50% DV)

📊 5.0× RDA — above typical dose 📚 27 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.15mg

Pantothenic Acid

10 mg (100% DV)

✅ 2.0× RDA — within safe limits 📚 2 studies — no high-quality reviews

RDA 5mg This product: 10mg

Iodine

75 mcg (50% DV)

✅ Within RDA (0.5× RDA of 0.15 mg) 📚 245 studies (Tier A: 4, B: 133)

RDA 0.15mg This product: 0.075mg UL 1.1mg

Zinc

7.5 mg (50% DV)

✅ Within RDA (0.7× RDA of 11 mg) 📚 263 studies (Tier A: 6, B: 134)

RDA 11mg This product: 7.5mg UL 40mg

Sodium

15 mg (1% DV)

Other Ingredients

Corn Syrup Sugar Water Gelatin Sodium Ascorbate Calcium D-Pantothenate Citric Acid DL-Alpha-Tocopheryl Acetate Niacinamide Zinc Sulfate Corn Starch Malic Acid Palm Oil Natural flavors Colors added Pyridoxine Hydrochloride Carnauba Wax Retinyl Acetate Folic Acid Biotin Cholecalciferol Potassium Iodide Cyanocobalamin

Label Claims — Verification

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Suggested use: Chew two gummies daily.

⚠️ Warnings & Precautions

Store in a cool, dry place, out of reach of children.

Do not use if imprinted seal under cap is broken or missing.

Caution: Some supplements may interact with certain medications. If you are taking any medication, please consult with your physician before taking this product.

🧪 Formulation Notes

Colors derived from natural sources - No synthetic dyes No yeast Gluten free

Additional Information

List No. 4040 L203 Cat. A767 5B105

Natural fruit flavors Key nutrients for daily nutritional support

Orange, Cherry & mixed Berry with other natural flavors

All natural flavors

Keep bottle tightly closed. Store in a cool, dry place, out of reach of children.

Multi adult gummies are made to Nature Made’s guaranteed purity and potency standards.

Product Details

UPC / SKU 0 31604 04040 6

DSLD Entry Date 2018-08-31

Product Type Multi-Vitamin and Mineral (MVM)

Form Gummy or Jelly

Brand Nature Made

DSLD ID 180149

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →