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Systemic-Care

product on market Tablet or Pill Xtendlife Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 34% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains biotin and calcium, which are supported by strong evidence for metabolic function and bone health. However, the overall evidence coverage for the specific ingredient profile is very limited. The product maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Systemic-Care
Open Full PDF View on NIH DSLD →
Details

Label Data

6 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
34%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
25 Calorie(s)
Total Fat
0.5 Gram(s) (1% DV)
Total Carbohydrates
4 Gram(s) (1% DV)
2992 mcg (997% DV)
99.7× RDA — above typical dose 27 studies (A:0, B:11)
Calcium
103 mg (10% DV)
Iron
0.5 mg (3% DV)
71 mg (18% DV)
Within RDA (0.2× RDA) 316 studies (A:8, B:159)
9 mg (60% DV)
Within RDA (0.8× RDA) 263 studies (A:6, B:134)
90 mcg (129% DV)
1.6× RDA — within safe limits 173 studies (A:0, B:67)
0.2 mg (10% DV)
Within RDA (0.2× RDA) 37 studies (A:0, B:11)
1.7 mg (85% DV)
Within RDA (0.7× RDA) 9 studies — no high-quality reviews
110 mcg (92% DV)
3.1× RDA — above typical dose 199 studies (A:1, B:55)
58 mcg (77% DV)
1.3× RDA — within safe limits 3 studies — no high-quality reviews
Gymnema leaf extract
550 mg
Bitter Melon Fruit Extract
450 mg
Market median: 260.0mg (249 products) 158 studies (A:4, B:61)
Indian Kino Tree stem extract
300 mg
Market median: 250.0mg (562 products) 55 studies (A:0, B:19)
300 mg
Market median: 500.0mg (283 products) 174 studies (A:0, B:62)
Market median: 300.0mg (214 products) 25 studies (A:0, B:6)
295 mg
Market median: 500.0mg (19 products)
Luteolin
268 mg
235 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Betain HCl
178 mg
120 mg
Market median: 200.0mg (136 products) 3 studies — no high-quality reviews
Myricetin
105 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
Amylase
60 mg
Lipase
60 mg
MSM
60 mg
Market median: 1000.0mg (2 products)
Nigella seed extract
30 mg
Piperine
28 mg

Other Ingredients

Microcrystalline Cellulose Dextrose Enteric Coating Maltodextrin Silicon Dioxide Sodium Carboxymethyl Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions For Use Adults: 6 tablets per day. Either take 6 tablets first thing in the morning or split into 2 doses, in the morning and later in the day.

Warnings & Precautions

Contains peanut.

Formulation Notes

Contains peanut.

Does not contain dairy, gluten, soy or shellfish.

Additional Information

Store in a cool, dry place.

L1029-13

Best quality guarantee Advanced formula enteric coated

Made in New Zealand

Metadata

Product Details

DSLD Entry Date2018-02-23
Product TypeOther Combinations
FormTablet or Pill
DSLD ID82182
Data Updated2026-04-11
Research

Research Evidence

849
Research Sources
56
Avg Quality
450
Meta Analysis
152
Rct
137
Systematic Review
73
Clinical Trial
11
Regulatory Source
7
Other
7
Guideline
3
Openfda Safety
2
Cochrane Review
2
Observational
A Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD)
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin and mineral supplementation for maintaining cognitive function in cognitively healthy people in mid and late life
Meta Analysis The Cochrane database of systematic reviews 2018 PubMed DOI
A Calcium supplementation during pregnancy for preventing hypertensive disorders and related problems
Meta Analysis The Cochrane database of systematic reviews 2025 PubMed DOI
A Dietary calcium supplementation for preventing colorectal cancer and adenomatous polyps
Systematic Review The Cochrane database of systematic reviews 2008 PubMed DOI
A Calcium and vitamin D for increasing bone mineral density in premenopausal women
Systematic Review The Cochrane database of systematic reviews 2023 PubMed DOI
A Dietary sodium, sodium-to-potassium ratio, and risk of stroke: A systematic review and nonlinear dose-response meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2019 PubMed DOI
A The association between circulating magnesium and clinically relevant outcomes in patients with chronic kidney disease: A systematic review and meta-analysis
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2021 PubMed DOI
A Calcium channel blockers versus other classes of drugs for hypertension
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
View all evidence for Electrolytes →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.