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Bone Builder Active

product on market Tablet or Pill Metagenics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 53% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains calcium and vitamin D, which have strong evidence for supporting bone mineral density. Vitamin C and niacin provide additional metabolic support, though evidence coverage for this specific combination is limited. The profile maintains a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Bone Builder Active
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Tablet(s)
Serving Size
60
Servings
Other Combinations
Product Type
53%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Total Carbohydrates
1 Gram(s) (1% DV)
Vitamin C
249 mg (277% DV)
5 mcg (25% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
18 mg (113% DV)
1.3× RDA — within safe limits 196 studies (A:5, B:63)
Calcium
610 mg (47% DV)
350 mg (28% DV)
Within RDA (0.5× RDA) 13 studies (A:0, B:3)
110 mg (26% DV)
Within RDA (0.3× RDA) 316 studies (A:8, B:159)
7.5 mg (68% DV)
Within RDA (0.7× RDA) 263 studies (A:6, B:134)
0.99 mg (110% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
0.48 mg (21% DV)
Within RDA (0.2× RDA) 9 studies — no high-quality reviews
120 mcg (343% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
Microcrystalline Hydroxyapatite Concentrate
1.34 Gram(s)
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Horsetail Aerial Parts Extract
75 mg
195 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Microcrystalline Hydroxyapatite Concentrate Dicalcium Phosphate Magnesium Bisglycinate Microcrystalline Cellulose Calcium Ascorbate Niacinamide Ascorbate Ascorbic Acid Sodium Ascorbate Magnesium Ascorbate L-Lysine Hydrochloride Ascorbyl Palmitate Potassium Ascorbate Citrus Bioflavonoid Complex Tetrasodium Pyrophosphate Alpha-D-Ribofuranose L-Cysteine Hydrochloride Xylitol L-Glutathione Glucosamine Sulfate Potassium Chloride Croscarmellose Sodium Horsetail Extract Silica Zinc Citrate Magnesium Stearate Copper Lysinate Hydrochloride Chromium Citrate Cholecalciferol Citric Acid Magnesium Citrate Boric Acid Niacinamide Hypromellose Medium Chain Triglyceride Hydroxypropyl Cellulose
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take three tablets once daily or as directed by your healthcare practitioner.

Warnings & Precautions

Caution: If pregnant, nursing, or taking medication, consult your healthcare practitioner before use.

Keep out of reach of children.

Tamper evident: Do not use if safety seal is missing or broken.

Practitioner Exclusive

Contains: Crustacean shellfish (crab shells, shrimp).

Formulation Notes

Bone Builder Active provides bone health support with microcrystalline hydroxyapatite concentrate (MCHC), a highly absorbable crystalline compound that provides naturally-occurring components of bone and is backed by more than 30 years of research. MCHC contains naturally occurring calcium, phosphorus, trace amounts of other minerals, bone growth factors, and collagen and other vital bone proteins. This well-rounded formula is designed to support bone mineral density, and also features vitamin D, additional minerals, glucosamine, and vitamin C for enhanced bone and joint health support.

This product is non-GMO and gluten-free.

Certified Gluten Free GFCO.org

Enhanced bone support

Additional Information

Storage: Keep tightly closed in a cool, dry place.

Certified Gluten Free GFCO.org

Metadata

Product Details

UPC / SKU7 55571 01320 0
DSLD Entry Date2025-02-23
Product TypeOther Combinations
FormTablet or Pill
BrandMetagenics
DSLD ID323333
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.