🟢 85/100

This product is generally safe

  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • Proprietary Super B Blend: 30mg is 1.5× the Tolerable Upper Intake Level (20mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 71% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
⚠️ Proprietary Super B Blend: 30mg is 1.5× the Tolerable Upper Intake Level (20mg)
ℹ️ Contains proprietary blend — exact ingredient amounts not disclosed

Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
71% Evidence Coverage

Supplement Facts — Evidence Check

25 mg (2083% DV)
📊 20.8× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 25mg
25 mg (1923% DV)
📊 19.2× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 25mg
35 mg (219% DV)
✅ 2.5× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 35mg UL 35mg
25 mg (1471% DV)
📊 19.2× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 25mg UL 100mg
667 mcg DFE (167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 667mg UL 1.0mg
100 mcg (4167% DV)
📊 41.7× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.1mg
150 mcg (500% DV)
📊 5.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.15mg
15 mg (300% DV)
✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 15mg
Calcium
143 mg (11% DV)
10 mg (2% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 10mg
3 mg (27% DV)
✅ Within RDA (0.3× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 3mg UL 40mg
50 mcg (91% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
0.65 mg (28% DV)
✅ Within RDA (0.3× RDA of 2.3 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 0.65mg UL 11mg
⚠️ Exceeds Tolerable Upper Intake Level by 1.5× (UL: 20 mg) 📚 2 studies — no high-quality reviews
This product: 30mg UL 20mg

Label Claims — Verification

Nutrient
All Other
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Take 2 tablets daily with a meal.

🧪 Formulation Notes

Promotes a positive outlook and healthy energy levels Supports normal cardiovascular health

Additional Information

Seed to Seal Young Living quality commitment Est. 1994

Product Details

DSLD Entry Date 2022-08-23
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 273852
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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