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EstroFactors

product on market Tablet or Pill Metagenics Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 62% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile contains a blend of fat-soluble vitamins and vitamin B6, which are supported by strong evidence for maintaining bone health and immune function. These nutrients play essential roles in cellular regulation and metabolic processes. Current research indicates a high safety profile for these ingredients when taken within recommended dosages.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for EstroFactors
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
62%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin A
2500 IU (50% DV)
200 IU (50% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
200 IU (667% DV)
8.9× RDA — above typical dose (UL: 1000 mg) 179 studies (A:3, B:90)
40 mcg (50% DV)
Within RDA (0.3× RDA) 275 studies (A:9, B:175)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
800 mcg (200% DV)
2.0× RDA — within safe limits 226 studies (A:10, B:105)
30 mcg (500% DV)
12.5× RDA — above typical dose 139 studies (A:1, B:44)
Isoflavones
100 mg
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
Rosemary (Rosmarinus officinalis) Leaf Extract
200 mg
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
Market median: 496.0mg (192 products) 20 studies — no high-quality reviews
Chrysin
90 mg

Other Ingredients

Stearic Acid Microcrystalline Cellulose Calcium Silicate Croscarmellose Sodium Silica Magnesium Stearate Coating
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: Take three tablets daily with a meal or as directed by your healthcare practitioner.

Warnings & Precautions

CAUTION: Not recommended for pregnant or nursing women. The effectiveness of oral contraceptives for birth control cannot be ensured while taking this product. If taking medication, consult your healthcare practitioner before use.

Keep out of the reach of children.

WARNING: Excess vitamin A intake may be toxic and may increase the risk of birth defects. Pregnant women and women who may become pregnant should not exceed 5000 IU of preformed vitamin A (retinyl palmitate) per day.

Additional Information

This unique formula features natural selective estrogen receptor modulators (SERMs) and L-5-methyl tetrahydrofolate to support multiple aspects of estrogen metabolism.

Genetic Potential Through Nutrition

METABOTANICA(R) METHOD

Promotes Estrogen Balance, Reduces Menopausal Symptoms

LES012J2

PROD. ESTRFAC

Lot# 0310130 Exp: 0512

Metadata

Product Details

UPC / SKU7 55571 01585 3
DSLD Entry Date2013-10-25
Product TypeOther Combinations
FormTablet or Pill
BrandMetagenics
DSLD ID26818
Data Updated2026-04-11
Research

Research Evidence

337
Research Sources
54
Avg Quality
161
Meta Analysis
68
Systematic Review
51
Rct
48
Clinical Trial
2
Other
2
Regulatory Source
1
Narrative Review
1
Cochrane Review
1
Guideline
1
Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011 PubMed DOI
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011 PubMed DOI
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019 PubMed DOI
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016 PubMed DOI
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023 PubMed DOI
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019 PubMed DOI
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
View all evidence for Vitamin A →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.