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Cal Matrix

product on market Tablet or Pill Metagenics Safety: 98/100
98/100

This product looks safe

  • Niacin: 36mg is 1.0× the Tolerable Upper Intake Level (35mg)
  • 57% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula combines calcium and phosphorus, which have strong evidence for supporting bone mineral density. Vitamin D and C further assist in calcium absorption and connective tissue health. Research indicates these nutrients are generally safe and effective for skeletal maintenance.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 36mg is 1.0× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Cal Matrix
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Tablet(s)
Serving Size
90
Servings
Other Combinations
Product Type
57%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
500 mg (833% DV)
134 IU (34% DV)
Within RDA (0.2× RDA) 608 studies (A:16, B:251)
36 mg (180% DV)
Exceeds UL by 1.0× (UL: 35 mg) 196 studies (A:5, B:63)
Calcium
1224 mg (122% DV)
774 mg (77% DV)
1.1× RDA — within safe limits 13 studies (A:0, B:3)
220 mg (55% DV)
Within RDA (0.5× RDA) 316 studies (A:8, B:159)
15 mg (100% DV)
1.4× RDA — within safe limits 263 studies (A:6, B:134)
2 mg (100% DV)
2.2× RDA — within safe limits 37 studies (A:0, B:11)
1 mg (50% DV)
Within RDA (0.4× RDA) 9 studies — no high-quality reviews
240 mcg (200% DV)
6.9× RDA — above typical dose 199 studies (A:1, B:55)
MCHC
2688 mg
Horsetail
150 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
390 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Microcrystalline hydroxyapatite Dicalcium Phosphate Magnesium Glycinate Stearic Acid Ultra Potent-C(R) Glucosamine sulfate potassium chloride Croscarmellose Sodium Cellulose Microcrystalline Cellulose Horsetail extract Zinc Glycinate Silica Magnesium Stearate Copper Glycinate Chromium Nicotinate Glycinate Boron Citrate Manganese Glycinate Cholecalciferol Niacinamide Ascorbate Coating Ingredients
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: Take two tablets up to three times daily or as directed by your healthcare practitioner.

Warnings & Precautions

CAUTION: This product is not suitable for individuals with shellfish allergies.

Keep out of the reach of children.

If pregnant, nursing, or taking medication, consult your healthcare practitioner before use.

Contains: crustacean shellfish (crabshells, shrimp).

Formulation Notes

Cal Matrix offers comprehensive bone nourishment with vitamin D and calcium-rich microcrystalline hydroxyapatite concentrate. It also features the added benefits of glucosamine sulfate, select minerals, and vitamin C for collagen, bone matrix, and joint support.

Formulated to Exclude: Wheat, gluten, corn protein, soy, dairy products, nuts, tree nuts, colors, artificial sweeteners, and preservatives.

Contains: crustacean shellfish (crabshells, shrimp).

Additional Information

Lot#: 129044 12/11

PROD. CA004

Genetic Potential Through Nutrition

Nutritional Support for Bone and Joint Integrity

LCA014N1

Metadata

Product Details

UPC / SKU7 55571 01320 9
DSLD Entry Date2013-11-25
Product TypeOther Combinations
FormTablet or Pill
BrandMetagenics
DSLD ID26786
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
View all evidence for Vitamin C →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.