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HeartBeat

product on market Tablet or Pill NaturesPlus Safety: 85/100
85/100

This product is generally safe

  • Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)
  • Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 71% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The B-vitamin complex, including folate and B12, is supported by strong evidence for managing homocysteine levels to support cardiovascular health. Calcium provides essential structural support, though its role in heart-specific supplementation varies by individual need. Overall, these ingredients have a well-documented safety profile for general use.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 40mg is 1.1× the Tolerable Upper Intake Level (35mg)

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for HeartBeat
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Heart-Shaped Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

40 mg NE (250% DV)
Exceeds UL by 1.1× (UL: 35 mg) 196 studies (A:5, B:63)
4 mg (235% DV)
3.1× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg DFE (100% DV)
Exceeds UL by 400.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
20 mcg (833% DV)
8.3× RDA — above typical dose 139 studies (A:1, B:44)
Calcium
50 mg (4% DV)
25 mg (6% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
70 mcg (127% DV)
1.3× RDA — within safe limits 173 studies (A:0, B:67)
Potassium
99 mg (2% DV)
CardioAid Plant Sterols standardized extract
400 mg
Proprietary Heart Health Botanical Complex
200 mg
75 mg
Market median: 500.0mg (180 products) 5 studies (A:0, B:1)
75 mg
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
25 mg
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)
10 mg
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)

Other Ingredients

Microcrystalline Cellulose Potassium Chloride Calcium Carbonate Vegetable Cellulose Magnesium Oxide Stearic Acid Magnesium Stearate Silica Pharmaceutical Glaze
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement for adults, three tablets once daily.

Warnings & Precautions

Keep out of reach of children.

Formulation Notes

Cardiovascular support Nutritionally supports every aspect of cardiovascular wellness

Nutritional support for a healthy heart

Gluten Free

Vegetarian

Contains no milk, egg, fish, crustacean shellfish, tree nuts, wheat, peanuts or soy allergen. Contains no artificial colors or preservatives.

Additional Information

Keep tightly closed in a cool, dry place.

Metadata

Product Details

UPC / SKU0 97467 47421 5
DSLD Entry Date2021-05-22
Product TypeOther Combinations
FormTablet or Pill
BrandNaturesPlus
DSLD ID249811
Data Updated2026-04-11
Research

Research Evidence

241
Research Sources
55
Avg Quality
113
Meta Analysis
75
Systematic Review
32
Rct
11
Clinical Trial
3
Other
3
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013 PubMed DOI
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014 PubMed DOI
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024 PubMed DOI
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010 PubMed DOI
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010 PubMed DOI
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014 PubMed DOI
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019 PubMed DOI
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016 PubMed DOI
View all evidence for Niacin →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.