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MitoTone Plus

product on market Capsule Douglas Laboratories Safety: 98/100
98/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 69% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains a complex of B vitamins, which are essential for cellular energy production and metabolic function. There is strong clinical evidence supporting the role of these nutrients in maintaining mitochondrial health and neurological function. The profile maintains a high safety score with minimal risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for MitoTone Plus
Open Full PDF View on NIH DSLD →
Details

Label Data

3 Vegetarian Capsule(s)
Serving Size
30
Servings
Other Combinations
Product Type
69%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mg (1667% DV)
16.7× RDA — above typical dose 76 studies (A:0, B:33)
20 mg (1538% DV)
15.4× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (313% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
45 mg (2647% DV)
34.6× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
1000 mcg (41667% DV)
416.7× RDA — above typical dose 139 studies (A:1, B:44)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
50 mg (12% DV)
Within RDA (0.1× RDA) 316 studies (A:8, B:159)
Sodium
56 mg (2% DV)
Market median: 500.0mg (861 products) 61 studies (A:4, B:13)
Market median: 5.0mg (298 products) 705 studies (A:5, B:123)
Market median: 4002.0mg (1 products) 21 studies (A:0, B:2)
Malic Acid
160 mg
N-Acetyl-L-Cysteine
100 mg
Market median: 200.0mg (198 products) 6 studies — no high-quality reviews
Market median: 100.0mg (283 products) 144 studies (A:1, B:64)
Market median: 167.0mg (311 products) 183 studies (A:0, B:65)

Other Ingredients

Hydroxypropyl Methylcellulose Ascorbyl Palmitate Silica
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Usage: Adults take 3 capsule daily with food or as directed by a healthcare professional.

Warnings & Precautions

Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your healthcare professional before using this product.

Keep out of the reach of children.

Use only if safety seal is intact.

Formulation Notes

Gluten-free, Non-GMO

Mitochondrial health

Additional Information

Store in a cool, dry place.

Contents may not fill bottle in order to accommodate required labeling. Please rely on stated quantity. Scan to learn about our manufacturing excellence

Metadata

Product Details

UPC / SKU3 10539 97800 9
DSLD Entry Date2020-08-23
Product TypeOther Combinations
FormCapsule
BrandDouglas Laboratories
DSLD ID232823
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.