🟢 94/100

This product looks safe

  • Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
  • Zinc: 50mg is 1.2× the Tolerable Upper Intake Level (40mg)
  • 85% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 500mg is 14.3× the Tolerable Upper Intake Level (35mg)
⚠️ Zinc: 50mg is 1.2× the Tolerable Upper Intake Level (40mg)

Label Data

6 Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
85% Evidence Coverage

Supplement Facts — Evidence Check

Vitamin A
50000 IU (1000% DV)
2000 IU (500% DV)
📊 3.3× RDA — above typical dose (UL: 0.1 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.05mg UL 0.1mg
18 IU (60% DV)
✅ Within RDA (0.8× RDA of 15 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 12.06mg UL 1000mg
500 mg (2500% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 14.3× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 500mg UL 35mg
50 mg (2500% DV)
📊 38.5× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 50mg UL 100mg
2500 mg (25000% DV)
📊 500.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 2500mg
50 mg (333% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.2× (UL: 40 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 50mg UL 40mg
100 mcg (143% DV)
✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.1mg UL 0.4mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
400 mcg (333% DV)
📊 11.4× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.4mg
500 mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 500mg
📊 8.0× RDA — above typical dose (UL: 1000 mg) 📚 177 studies (Tier A: 3, B: 90)
RDA 15mg This product: 120mg UL 1000mg
500 mcg
📊 16.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.5mg

Other Ingredients

Microcrystalline Cellulose Silicon Dioxide Vegetable Stearate

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Recommended Use: As a dietary supplement, take six capsules per day, or as directed by your health care practitioner.

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

🧪 Formulation Notes

Does not contain gluten.

Additional Information

STORE IN A COOL DRY PLACE.

Guaranteed GMP COMPLIANT Products

Manufactured in an NSF GMP Registered Facility

Notice: Color, size or shape may appear different between lots.

ACN180

Natural Acne Support

For Professional Use Only

Product Details

UPC / SKU 8 79452 00364 4
DSLD Entry Date 2013-07-25
Product Type Other Combinations
Form Capsule
DSLD ID 22578
Data Updated 2026-04-11

Research Evidence

337 Research Sources
54 Avg Quality Score
161 Meta Analysis
68 Systematic Review
51 Rct
48 Clinical Trial
2 Other
2 Regulatory Source
1 Narrative Review
1 Cochrane Review
1 Guideline
1 Openfda Safety
A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age
Meta Analysis The Cochrane database of systematic reviews 2017
A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection
Meta Analysis The Cochrane database of systematic reviews 2011
A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis
Meta Analysis BMJ (Clinical research ed.) 2011
A Fortification of staple foods with vitamin A for vitamin A deficiency
Systematic Review The Cochrane database of systematic reviews 2019
A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age
Narrative Review The Cochrane database of systematic reviews 2016
A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa
Meta Analysis The Cochrane database of systematic reviews 2020
A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Journal of sport and health science 2023
A Food fortification with multiple micronutrients: impact on health outcomes in general population
Meta Analysis The Cochrane database of systematic reviews 2019
A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age
Meta Analysis The Cochrane database of systematic reviews 2024
View all evidence for Vitamin A →

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