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Ortho Bone

product on market Capsule AOR Advanced Orthomolecular Research Ultra Safety: 95/100
95/100

This product looks safe

  • Folate: 670mg is 670.0× the Tolerable Upper Intake Level (1.0mg)
  • Magnesium: 420mg is 1.2× the Tolerable Upper Intake Level (350mg)
  • 67% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

Vitamin D3 and K2 have strong evidence for supporting bone mineral density and calcium regulation. Vitamin C and folate contribute to collagen synthesis and cellular function, though their roles in bone health are secondary. The ingredient profile is associated with a high safety score.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 670mg is 670.0× the Tolerable Upper Intake Level (1.0mg)

Magnesium: 420mg is 1.2× the Tolerable Upper Intake Level (350mg)

Label

Product Label

Label for Ortho Bone
Open Full PDF View on NIH DSLD →
Details

Label Data

5 Capsule(s)
Serving Size
30
Servings
Multi-Vitamin and Mineral (MVM)
Product Type
67%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Vitamin C
90 mg (100% DV)
13 mcg (65% DV)
Within RDA (0.9× RDA) 608 studies (A:16, B:251)
25 mcg (125% DV)
1.7× RDA — within safe limits 608 studies (A:16, B:251)
120 mcg (100% DV)
Within RDA (1.0× RDA) 275 studies (A:9, B:175)
670 mcg DFE (168% DV)
Exceeds UL by 670.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
24 mcg (1000% DV)
10.0× RDA — above typical dose 139 studies (A:1, B:44)
Calcium
1000 mg (77% DV)
455 mg (36% DV)
Within RDA (0.7× RDA) 13 studies (A:0, B:3)
420 NP (100% DV)
Exceeds UL by 1.2× (UL: 350 mg) 316 studies (A:8, B:159)
11 mg (100% DV)
Within RDA (1.0× RDA) 263 studies (A:6, B:134)
1 mg (111% DV)
1.1× RDA — within safe limits 37 studies (A:0, B:11)
2.3 mg (100% DV)
Within RDA (1.0× RDA) 9 studies — no high-quality reviews
Ossein Microcrystalline Hydroxyapatite (MCHA) Complex
4545 mg
35 mg
Market median: 108.0mg (8 products) 9 studies (A:0, B:4)
700 mcg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Microcrystalline Cellulose Hydroxypropyl Cellulose Coconut Oil Sunflower Oil Acacia Gum Sucrose DL-Alpha-Tocopherol Tricalcium Phosphate Capsule Corn Starch Corn Maltodextrin Citric Acid Glycine L-Aspartic Acid Silicon Dioxide Medium Chain Triglycerides Magnesium Trisilicate Sodium Stearyl Fumarate Rice Starch Soy Starch
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: Take 5 capsules twice daily, with meals to facilitate maximum absorption, taking second dose with the last meal or snack of the day, or as directed by a qualified health care practitioner.

Warnings & Precautions

Do not use if safety seal is broken

Warning: Do not use if you are pregnant or lactating. Consult your physician if you have a medical condition, or if you’re taking any medication (such as blood thinners).

Keep out of reach of children.

Caution: Some people may experience diarrhea.

Contains: soy, tree nuts (coconut).

To report a serious adverse event or obtain product information, call 1-866-215-0450

Formulation Notes

GMP Manufacturing Quality assured Independent testing

Discussion: Ortho Bone is a multi-nutrient combination that features a superior calcium source to support healthy bone structure. It has ossein microcrystalline hydroxyapatite complex (MCHA complex, Bone Meal), a lyophilized extract of bovine bone, which promotes the normal retention of the intact microcrystalline structure of whole bone. The MCHA complex in Ortho Bone is derived from New Zealand pasture-fed, free-range livestock not subjected to routine antibiotics or rBGH.

Guaranteed free of bovine spongiform encephalopathy.

Made without wheat, gluten, peanuts, sesame seeds, sulfites, mustard, dairy or eggs.

With MCHA, a well tolerated and effective form of calcium

Non-GMO Gluten free

Additional Information

Store tightly sealed in a cool, dry place

AOR guarantees that all ingredients have been declared on the label.

MyBlueprint

Product of Canada

Metadata

Product Details

UPC / SKU6 24917 08078 0
DSLD Entry Date2020-03-24
Product TypeMulti-Vitamin and Mineral (MVM)
FormCapsule
DSLD ID214807
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
A Vitamin C supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for the primary prevention of cardiovascular disease
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin C for preventing and treating the common cold
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin C for preventing and treating pneumonia
Meta Analysis The Cochrane database of systematic reviews 2013 PubMed DOI
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Meta Analysis The Cochrane database of systematic reviews 2020 PubMed DOI
A Vitamin C supplementation for prevention and treatment of pneumonia
Systematic Review The Cochrane database of systematic reviews 2021 PubMed DOI
A Nutritional interventions for preventing and treating pressure ulcers
Meta Analysis The Cochrane database of systematic reviews 2024 PubMed DOI
A Does Vitamin C Supplementation Provide a Protective Effect in Periodontal Health? A Systematic Review and Meta-Analysis
Meta Analysis International journal of molecular sciences 2024 PubMed DOI
A Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.