🟢 94/100

This product looks safe

  • Niacin: 70mg is 2.0× the Tolerable Upper Intake Level (35mg)
  • Folate: 1333mg is 1333.0× the Tolerable Upper Intake Level (1.0mg)
  • 62% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 70mg is 2.0× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 1333mg is 1333.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
62% Evidence Coverage

Supplement Facts — Evidence Check

70 mg (350% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 2.0× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 70mg UL 35mg
1333 mcg DFE (200% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1333.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 1333mg UL 1.0mg
12 mcg (200% DV)
📊 5.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.012mg
200 mcg (66% DV)
📊 6.7× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.2mg
200 mg (2000% DV)
📊 40.0× RDA — above typical dose 📚 1 studies — no high-quality reviews
RDA 5mg This product: 200mg
Calcium
250 mg (20% DV)
Iron
4 mg (22% DV)
300 mcg (200% DV)
✅ 2.0× RDA — within safe limits 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.3mg UL 1.1mg
30 mg (200% DV)
✅ 2.7× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 30mg UL 40mg
10 mg (500% DV)
📊 4.3× RDA — above typical dose (UL: 11 mg) 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 10mg UL 11mg
✅ 1.8× RDA — within safe limits 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 1000mg UL 3500mg
250 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 250mg
60 mg
📊 Market median: 500.0mg (9 products)
This product: 60mg

Other Ingredients

Microcrystalline Cellulose Croscarmellose Sodium Stearic Acid Magnesium Stearate Silica Brewers Yeast Pharmaceutical Glaze Talc

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (86% of products) Nutrient (36% of products)

Target Groups

Adult (18 - 50 Years)

Product Information

📋 Directions for Use

Directions: Adults - take two tablets daily, preferably with food, as a dietary supplement.

⚠️ Warnings & Precautions

Warning: Accidental overdose of iron containing products is a leading cause of fatal poisoning in children under 6. In case of accidental overdose, call a doctor or poison control center immediately. Poison control center: 1-800-222-1222

Warning: If you are pregnant, nursing, taking any medications or planning any medical procedure, consult your physician before use.

Discontinue use and consult your physician if any adverse reactions occur.

Keep out of reach of children.

Tamper-Evident Seal: Do not use product if seal appears tampered.

🧪 Formulation Notes

May support healthy hair

Guaranteed no added: sugar, starch, soy, corn, wheat, dairy, fish, tree nuts, peanuts, egg, fragrance, artificial colors, flavors, preservatives, crustacean/shellfish, sodium free.

Soy free

Additional Information

Mason Guarantee Laboratory Tested cGMP Certified Good Manufacturing Practice Certified

Mason Natural Est. 1967

Store in a dry place under controlled room temperature: 20 degrees - 25 degrees C (68 degrees - 77 degrees F).

Product Details

UPC / SKU 3 11845 12275 9
DSLD Entry Date 2020-02-26
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 214453
Data Updated 2026-04-11

Research Evidence

241 Research Sources
55 Avg Quality Score
113 Meta Analysis
75 Systematic Review
32 Rct
11 Clinical Trial
3 Other
3 Regulatory Source
1 Cochrane Review
1 Narrative Review
1 Openfda Safety
A Niacin for primary and secondary prevention of cardiovascular events
Meta Analysis The Cochrane database of systematic reviews 2017
A Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases
Meta Analysis BMJ (Clinical research ed.) 2013
A Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Meta Analysis BMJ (Clinical research ed.) 2014
A A terminal metabolite of niacin promotes vascular inflammation and contributes to cardiovascular disease risk
Meta Analysis Nature medicine 2024
A Meta-analysis and imputation refines the association of 15q25 with smoking quantity
Meta Analysis Nature genetics 2010
A Genome-wide meta-analyses identify multiple loci associated with smoking behavior
Meta Analysis Nature genetics 2010
A Antidepressants for smoking cessation
Meta Analysis The Cochrane database of systematic reviews 2014
A Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne
Meta Analysis The Cochrane database of systematic reviews 2020
B Assessment of the Role of Niacin in Managing Cardiovascular Disease Outcomes: A Systematic Review and Meta-analysis
Meta Analysis JAMA network open 2019
B Association Between Lowering LDL-C and Cardiovascular Risk Reduction Among Different Therapeutic Interventions: A Systematic Review and Meta-analysis
Meta Analysis JAMA 2016
View all evidence for Niacin →

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