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Estro Support ES

product on market Tablet or Pill 21st Century Safety: 98/100
98/100

This product looks safe

  • Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
  • 60% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B-vitamins and Vitamin E, which support cellular energy metabolism and antioxidant protection. Research evidence for these ingredients is generally strong, though the specific combination for estrogen support has limited clinical coverage. The profile maintains a high safety score with no significant concerns noted.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Estro Support ES
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
60%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

20 mg (134% DV)
1.3× RDA — within safe limits 179 studies (A:3, B:90)
5 mg (417% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
5 mg (385% DV)
3.8× RDA — above typical dose 13 studies (A:0, B:1)
20 mg (125% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
25 mg (1471% DV)
19.2× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
667 mg DFE (167% DV)
Exceeds UL by 667.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
25 mcg (1042% DV)
10.4× RDA — above typical dose 139 studies (A:1, B:44)
Calcium
200 mg (15% DV)
70 mcg (127% DV)
1.3× RDA — within safe limits 173 studies (A:0, B:67)
120 mcg (343% DV)
3.4× RDA — above typical dose 199 studies (A:1, B:55)
1.5 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews
Estro Support Herbal Blend
200 mg
purified Isoflavones
80 mg
Market median: 80.0mg (136 products)
Cranberry
300 mg

Other Ingredients

Maltodextrin Croscarmellose Sodium Cellulose Silicon Dioxide Stearic Acid Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Directions: As a dietary supplement, adults take one (1) tablet with any meal, twice daily or as directed by a healthcare provider. Do not exceed recommended dosage.

Warnings & Precautions

Do not exceed recommended dosage.

Warning: Consult a healthcare provider prior to use if pregnant, nursing, on medications, have a medical condition or are planning a medical procedure.

Stop use and contact a physician if adverse reactions occur.

Keep out of reach of children.

Do not use if product appears to be tampered with or seal is broken.

Contains soy.

Formulation Notes

No added Sugar, Yeast, Preservatives or Artificial Flavors.

Gluten free

Vitamins, minerals and herbs help to support the needs of women.

Contains soy.

Additional Information

Individual results may vary.

Store at room temperature.

Extra strength Compare vs. Estroven Extra Strength

Gluten free

Guaranteed quality Laboratory tested

Metadata

Product Details

UPC / SKU7 40985 27007 3
DSLD Entry Date2019-10-23
Product TypeOther Combinations
FormTablet or Pill
Brand21st Century
DSLD ID207388
Data Updated2026-04-11
Research

Research Evidence

253
Research Sources
55
Avg Quality
128
Meta Analysis
52
Systematic Review
41
Rct
24
Clinical Trial
3
Regulatory Source
1
Narrative Review
1
Other
1
Guideline
1
Openfda Safety
A Vitamin E supplementation in pregnancy
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Systematic Review The Cochrane database of systematic reviews 2017 PubMed DOI
A Vitamin E for Alzheimer's disease and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2008 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2012 PubMed DOI
A Exercise for intermittent claudication
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
A Effects of vitamin E supplementation on the risk and progression of AD: a systematic review and meta-analysis
Meta Analysis Nutritional neuroscience 2021 PubMed DOI
A Effect of vitamin E supplementation in rheumatoid arthritis: a systematic review and meta-analysis
Meta Analysis European journal of clinical nutrition 2023 PubMed DOI
A Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
Rct JAMA 2011 PubMed DOI
A Vitamin E for Alzheimer's dementia and mild cognitive impairment
Meta Analysis The Cochrane database of systematic reviews 2017 PubMed DOI
B Vitamin, Mineral, and Multivitamin Supplementation to Prevent Cardiovascular Disease and Cancer: US Preventive Services Task Force Recommendation Statement.
Guideline JAMA 2022 PubMed DOI
View all evidence for Vitamin E →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.