🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 53% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Capsule(s) Serving Size
Other Combinations Product Type
53% Evidence Coverage

Supplement Facts — Evidence Check

500 mcg (8333% DV)
📊 208.3× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.5mg
Calcium
100 mg (10% DV)
100 mcg (67% DV)
✅ Within RDA (0.7× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.1mg UL 1.1mg
150 mg (37% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 150mg
20 mg (133% DV)
✅ 1.8× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 20mg UL 40mg
150 mcg (214% DV)
✅ 2.7× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.15mg UL 0.4mg
1.5 mg (75% DV)
✅ 1.7× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 1.5mg UL 10mg
5 mg (250% DV)
✅ 2.2× RDA — within safe limits 📚 8 studies — no high-quality reviews
RDA 2.3mg This product: 5mg UL 11mg
200 mcg (167% DV)
📊 5.7× RDA — above typical dose 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.2mg
150 mcg (200% DV)
📊 3.3× RDA — above typical dose (UL: 2 mg) 📚 2 studies — no high-quality reviews
RDA 0.045mg This product: 0.15mg UL 2mg
Potassium
99 mg (3% DV)
Sulfur
50 mg
Cobalt
22 mcg
3 mg
📊 Market median: 3.0mg (58 products) 📚 2 studies — no high-quality reviews
This product: 3mg UL 20mg
3.5 mg
📊 Market median: 108.0mg (8 products) 📚 9 studies (Tier A: 0, B: 4)
This product: 3.5mg
200 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 200mg
200 mg
📊 Market median: 420.0mg (227 products)
Median 420.0mg This product: 200mg

Other Ingredients

Magnesium Stearate Silicon Dioxide Microcrystalline Cellulose

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (89% of products) Nutrient (56% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Dairy Free Sugar Free

Product Information

📋 Directions for Use

Recommended Use: As a dietary supplement, one to three (1-3) capsules preferably between meals, or as directed by a physician.

🧪 Formulation Notes

Free of: Yeast, wheat, corn, soy, milk, glutens, rice, sugar, starch, salt, preservatives, and artificial colorings or flavors.

Additional Information

Essential Minerals and Synergistic cofactors Optimized for Bioavailability

Its constituents and cofactors support the diverse metabolic pathways that facilitate life, from the survival level up through the most sophisticated organ functions. They activate enzymes that control thousands of metabolic pathways operating simultaneously in all the 100 trillion cells living in the body. They are essential to cell membranes, the dynamic action centers of the living cell. These essential elements become depleted from the body by stress, (emotional or chemical) poor diet, negative lifestyle factors, surgery, or tissue trauma.

WE USE USP/NF MATERIALS

AB(R)

1107

Product Details

UPC / SKU 6 90290 30310 5
DSLD Entry Date 2013-04-25
Product Type Other Combinations
Form Capsule
DSLD ID 20374
Data Updated 2026-04-11

Research Evidence

237 Research Sources
53 Avg Quality Score
83 Meta Analysis
74 Systematic Review
45 Rct
29 Clinical Trial
2 Guideline
2 Regulatory Source
1 Openfda Safety
A Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
Meta Analysis Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 2025
A Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
Meta Analysis Critical reviews in food science and nutrition 2019
A Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency
Systematic Review The Cochrane database of systematic reviews 2018
A Effects of Vitamin B12 Supplementation on Cognitive Function, Depressive Symptoms, and Fatigue: A Systematic Review, Meta-Analysis, and Meta-Regression
Meta Analysis Nutrients 2021
A Efficacy of different routes of vitamin B12 supplementation for the treatment of patients with vitamin B12 deficiency: A systematic review and network meta-analysis
Systematic Review Irish journal of medical science 2024
B Helicobacter pylori infection and micronutrient deficiency in pregnant women: a systematic review and meta-analysis
Meta Analysis BMJ open gastroenterology 2020
B Vitamin B12 supplementation during pregnancy for maternal and child health outcomes
Systematic Review The Cochrane database of systematic reviews 2024
B A comprehensive review and meta-regression analysis of randomized controlled trials examining the impact of vitamin B12 supplementation on homocysteine levels
Meta Analysis Nutrition reviews 2024
B Relationship between vitamin B12 levels and motor development: A systematic review
Systematic Review Clinical nutrition ESPEN 2024
B Vitamin B12, folate, and homocysteine in metabolic syndrome: a systematic review and meta-analysis
Meta Analysis Frontiers in endocrinology 2023
View all evidence for Vitamin B12 →

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