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Vitamin B-Complex

product on market Capsule Douglas Laboratories Safety: 97/100
97/100

This product looks safe

  • Niacin/Niacinamide: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 82% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

The B-complex ingredients, including thiamine, riboflavin, and folic acid, are supported by strong evidence for their roles in energy metabolism and neurological function. These nutrients facilitate cellular energy production and support red blood cell formation. The profile maintains a high safety score, indicating a low risk of adverse effects when used as directed.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin/Niacinamide: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Vitamin B-Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
82%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (2941% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
100 mcg (25% DV)
Within RDA (0.2× RDA) 226 studies (A:10, B:105)
50 mcg (833% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
50 mcg (17% DV)
1.7× RDA — within safe limits 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
50 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
50 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
23.5 mg
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)

Other Ingredients

Cellulose Gelatin Vegetable Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Usage: As a dietary supplement, adults take 1 capsule daily or as directed by your healthcare professional.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Formulation Notes

This product contains NO yeast, wheat gluten, soy protein, milk/dairy, corn, sodium, sugar, starch, artificial coloring, preservatives or flavoring.

Additional Information

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

Formula #80128

Metadata

Product Details

UPC / SKU3 10539 00096 0
DSLD Entry Date2012-06-01
Product TypeOther Combinations
FormCapsule
BrandDouglas Laboratories
DSLD ID9823
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.