84/100
This product is generally safe
- Niacin: 150mg is 4.3× the Tolerable Upper Intake Level (35mg)
- Folic Acid: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
- Contains proprietary blend — exact ingredient amounts not disclosed
- 75% of ingredients have research evidence
D
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6
· methodology
This supplement contains a complex of B vitamins that support energy metabolism and neurological function. There is strong research evidence for the roles of thiamine, riboflavin, and niacin in cellular health. However, the overall evidence coverage for this specific formulation is limited.
AI-generated summary based on research evidence. Not medical advice.
Alerts
Safety Alerts
Niacin: 150mg is 4.3× the Tolerable Upper Intake Level (35mg)
Folic Acid: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
Contains proprietary blend — exact ingredient amounts not disclosed
Details
Label Data
Botanical with Nutrients
Product Type
Ingredients
Supplement Facts — Evidence Check
125.0× RDA — above typical dose
76 studies (A:0, B:33)
115.4× RDA — above typical dose
13 studies (A:0, B:1)
Exceeds UL by 4.3× (UL: 35 mg)
196 studies (A:5, B:63)
76.9× RDA — above typical dose (UL: 100 mg)
114 studies (A:3, B:35)
Exceeds UL by 400.0× (UL: 1.0 mg)
226 studies (A:10, B:105)
62.5× RDA — above typical dose
139 studies (A:1, B:44)
5.0× RDA — above typical dose
27 studies (A:0, B:11)
Market median: 9.0mg (620 products)
2 studies — no high-quality reviews
Within RDA (0.3× RDA)
38 studies (A:1, B:7)
Market median: 500.0mg (9 products)
7 studies — no high-quality reviews
Market median: 550.0mg (217 products)
29 studies (A:0, B:5)
Other Ingredients
Vegetable Cellulose
Dicalcium Phosphate
Mannitol
Calcium Silicate
Vegetable Magnesium Stearate
Vegetable Cellulose Coating
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
DIRECTIONS: For adults, take one (1) caplet daily,preferably with a meal.
Warnings & Precautions
WARNING: If you are pregnant, nursing or taking any medications, consult your doctor before use. Discontinue use and consult your doctor if any adverse reactions occur. Keep out of reach of children. Store in a cool, dry place. Do not use if seal under cap is broken or missing.
Formulation Notes
No Artificial Color or Flavor, No Preservatives, No Sugar, No Starch, No Milk, No Lactose, No Gluten, No Wheat, No Yeast, No Fish. Sodium Free.
Vegetarian Vitamin Supplement
Additional Information
PROD. #585 B6059 09C
Promotes Energy Metabolism*
Supports Heart Health*
Vitamin World products are subject to critically stringent quality assurance analysis. Our state-of-the-art laboratory, manufacturing and packaging facilities insure the highest quality nutritional supplements money can buy. Your health & safety are our first priority!
QUALITY ASSURED
Get healthy.
Metadata
Product Details
UPC / SKU0 74312 73802 9
DSLD Entry Date2011-10-26
Product TypeBotanical with Nutrients
FormUnknown
Data Updated2026-04-11
Research
Research Evidence
B
Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review
The Cochrane database of systematic reviews
2013
PubMed
DOI
B
Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review
Nutritional neuroscience
2023
PubMed
DOI
B
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
B
Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis
Clinical nutrition (Edinburgh, Scotland)
2024
PubMed
DOI
B
Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review
Intensive care medicine
2022
PubMed
DOI
B
Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis
Pain medicine (Malden, Mass.)
2020
PubMed
DOI
B
Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis
Critical care medicine
2021
PubMed
DOI
B
The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis
Complementary therapies in medicine
2022
PubMed
DOI
B
Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis
Clinical and investigative medicine. Medecine clinique et experimentale
2023
PubMed
DOI
B
Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review
The Cochrane database of systematic reviews
2004
PubMed
View all evidence for Thiamine →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.
