🟢 98/100

This product looks safe

  • Folate: 1333mg is 1333.0× the Tolerable Upper Intake Level (1.0mg)
  • 60% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 1333mg is 1333.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Tablet(s) Serving Size
30 Servings
Other Combinations Product Type
60% Evidence Coverage

Supplement Facts — Evidence Check

3 mg (250% DV)
✅ 2.5× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 3mg
3 mg (231% DV)
✅ 2.3× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 3mg
32 mg NE (200% DV)
✅ 2.3× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 32mg UL 35mg
4 mg (235% DV)
📊 3.1× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 4mg UL 100mg
1333 mcg DFE (333% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1333.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 1333mg UL 1.0mg
12 mcg (500% DV)
📊 5.0× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.012mg
300 mcg (1000% DV)
📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.3mg
10 mg (200% DV)
✅ 2.0× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 10mg
Stress Support Blend
140 mg
Immune Support Blend
82 mg
organic Spinach
155 mg
Sunflower Lecithin
132 mg
organic Blueberry
95 mg
📊 Market median: 450.0mg (254 products) 📚 240 studies (Tier A: 0, B: 100)
This product: 8mg
📊 Market median: 250.0mg (337 products) 📚 125 studies (Tier A: 1, B: 41)
This product: 4mg

Other Ingredients

cultured Yeast organic Gum Acacia Silicon Dioxide organic Carnauba Wax organic Vegetable Coating

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Directions: Take two (2) tablets daily, with or without food.

⚠️ Warnings & Precautions

Warning: Consult your healthcare provider prior to use if you are pregnant, nursing, taking any medications or have any medical condition.

Keep out of reach of children.

Tamper Evident: Do not use if outer seal is broken or missing.

🧪 Formulation Notes

Does Not Contain: Wheat, gluten, salt, soy, starch, dairy, citrus, fish, animal derivatives, preservatives, artificial colors or artificial flavors.

Additional Information

Healthy heart & blood Immune support Energy & metabolism Stress response

Item No. VS-3339 2096246 HR 37

Visit www.vitaminshoppe.com or call 1-800-223-1216 for more information and to reorder.

Store in a cool, dry place.

Product Details

UPC / SKU 7 66536 03339 3
DSLD Entry Date 2017-11-20
Product Type Other Combinations
Form Tablet or Pill
Brand plnt
DSLD ID 80745
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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