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B-Complex 100

product on market Tablet or Pill Highland Laboratories Safety: 87/100
87/100

This product is generally safe

  • Niacinamide: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Contains proprietary blend — exact ingredient amounts not disclosed
  • 75% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B vitamins that support cellular energy metabolism and neurological function. Research provides strong evidence for the roles of thiamine, riboflavin, and niacin in metabolic processes. However, the overall evidence coverage for this specific product profile is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacinamide: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Contains proprietary blend — exact ingredient amounts not disclosed

Label

Product Label

Label for B-Complex 100
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Tablet(s)
Serving Size
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

100 mg (6666% DV)
83.3× RDA — above typical dose 76 studies (A:0, B:33)
100 mg (5882% DV)
76.9× RDA — above typical dose 13 studies (A:0, B:1)
100 mg (500% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
100 mg (5000% DV)
76.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg (100% DV)
Within RDA (1.0× RDA) 226 studies (A:10, B:105)
100 mcg (1666% DV)
41.7× RDA — above typical dose 139 studies (A:1, B:44)
100 mcg (33% DV)
3.3× RDA — above typical dose 27 studies (A:0, B:11)
100 mg (1000% DV)
20.0× RDA — above typical dose 2 studies — no high-quality reviews
100 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
50 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
45 mg
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
Proprietary Herbal Base
16 mg

Other Ingredients

Vegetable Stearate Calcium Phosphate Cellulose Silica Magnesium Stearate
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

One tablet daily, as a dietary supplement.

Warnings & Precautions

% Daily Value

Formulation Notes

No corn, soy, salt, yeast, wheat, milk & egg products, sugar, starch, or preservatives.

Our Continuous Release B-Complex tablets are formulated to provide a continuous and uniform release of B-Complex Vitamins over a 6 to 8 hour period.

Additional Information

Also available in 90 count

Herbal base - continuous release

GMP Quality Assured Earth Friendly

Each batch is laboratory tested to insure conformance to this rigid standard.

PR 230

Metadata

Product Details

UPC / SKU7 68305 23060 4
DSLD Entry Date2017-10-21
Product TypeOther Combinations
FormTablet or Pill
BrandHighland Laboratories
DSLD ID79477
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.