Home/ Supplements/ Thiamine/ Coenzyme-B B-50 Complex

Coenzyme-B B-50 Complex

product on market Capsule Vitabase Safety: 98/100
98/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • 71% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This complex contains B vitamins that support energy metabolism and neurological function. Research provides strong evidence for the roles of B1, B2, B6, and folate in cellular health. The formulation maintains a high safety profile based on available data.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for Coenzyme-B B-50 Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Vegetarian Capsule(s)
Serving Size
Other Combinations
Product Type
71%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (3333% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (2941% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
50 mg (250% DV)
Exceeds UL by 1.4× (UL: 35 mg) 196 studies (A:5, B:63)
50 mg (2500% DV)
38.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
800 mcg (200% DV)
2.0× RDA — within safe limits 226 studies (A:10, B:105)
50 mcg (833% DV)
20.8× RDA — above typical dose 139 studies (A:1, B:44)
200 mcg (67% DV)
6.7× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (500% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
25 mg
Market median: 125.0mg (294 products) 38 studies (A:1, B:7)
25 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
25 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
Cocarboxylase
5 mg
3.8× RDA — above typical dose 13 studies (A:0, B:1)
Pantethine
5 mg
3.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
10.4× RDA — above typical dose 139 studies (A:1, B:44)
Dibencozide
25 mcg

Other Ingredients

Cellulose Magnesium Stearate Silica
Claims

Label Claims — Verification

Unverified All Other
Info

Product Information

Directions for Use

Suggested Use: As a dietary supplement, adults take one (1) vegetarian capsule daily, or as directed by a health care professional.

Warnings & Precautions

Keep out of reach of children.

Formulation Notes

Contains No Added sugar, salt, dairy, yeast, wheat, corn, soy, preservatives, artificial colors or flavors.

Additional Information

Store in a cool, dry place and away from direct light.

The body converts dietary B vitamins and B vitamins in supplements into active forms via the liver. The metabolically active coenzyme forms of B vitamins delivered in our "Coenzyme B" formula do not need to be metabolized by the liver and are ready for immediate use by the body.

QUALITY AND POTENCY GUARANTEED.

Vb

Metadata

Product Details

DSLD Entry Date2012-03-23
Product TypeOther Combinations
FormCapsule
BrandVitabase
DSLD ID7040
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.