Signature Series Healthy Heart

product on market Capsule The Wellness Company 🟢 Safety: 97/100
Brand: The Wellness Company
🟢 97/100

This product looks safe

  • Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)
  • 82% of ingredients have research evidence
C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 340mg is 340.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Capsule(s) Serving Size
60 Servings
Other Combinations Product Type
82% Evidence Coverage

Supplement Facts — Evidence Check

2.5 mg (208% DV)
✅ 2.1× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 2.5mg
2.5 mg (192% DV)
✅ 1.9× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 2.5mg
3 mg (176% DV)
✅ 2.3× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 3mg UL 100mg
340 mcg DFE (85% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 340.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 340mg UL 1.0mg
100 mcg (333% DV)
📊 3.3× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.1mg
2.5 mg (50% DV)
✅ Within RDA (0.5× RDA of 5 mg) 📚 1 studies — no high-quality reviews
RDA 5mg This product: 2.5mg
50 mcg (91% DV)
✅ Within RDA (0.9× RDA of 0.055 mg) 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.05mg UL 0.4mg
D-Ribose
500 mg
350 mg
📊 Market median: 500.0mg (180 products) 📚 5 studies (Tier A: 0, B: 1)
This product: 350mg
200 mg
📊 Market median: 500.0mg (861 products) 📚 60 studies (Tier A: 4, B: 13)
This product: 200mg
25 mg
📊 Market median: 100.0mg (283 products) 📚 142 studies (Tier A: 1, B: 64)
This product: 25mg UL 1200mg

Other Ingredients

Hypromellose Silicon Dioxide Tricalcium Phosphate Stearic Acid Microcrystalline Cellulose

Label Claims — Verification

❓ All Other
❓ Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested use: As a dietary supplement, take two (2) capsules daily with 8-12 oz of water or as directed by a healthcare professional.

⚠️ Warnings & Precautions

Warning: Intended for use by adults 18 years of age and over. Keep out of reach of children.

Do not use if the seal under cap is broken or missing. Please consult your healthcare practitioner before taking and when using this supplement.

Allergen warning: This product was produced in a facility that may also process ingredients containing milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, and soybeans.

🧪 Formulation Notes

Our formulation is designed to support cardiovascular performance, circulation, and muscle mass for a healthy heart. This supplement was formulated by The Wellness Company's doctors as part of a naturalistic approach to health and wellness.

Gluten free Non GMO

Vegan

Cardiovascular & muscular strength

Additional Information

Healthy Heart by the Chief Medical Board

Learn more about our natural products and virtual care at www.TWC.health.

Vegan Made in the USA with ingredients from around the world

Designed & approved by the chief medical board

Product Details

UPC / SKU 8 50045 40514 4
DSLD Entry Date 2025-05-21
Product Type Other Combinations
Form Capsule
Brand The Wellness Company
DSLD ID 336267
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
PubMed DOI Cochrane
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
PubMed Cochrane
View all evidence for Thiamine →

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