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MasterMind

product on market Tablet or Pill Zahler Safety: 95/100
95/100

This product looks safe

  • Niacin: 70mg is 2.0× the Tolerable Upper Intake Level (35mg)
  • 86% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This profile combines SAMe, 5-HTP, and L-Tryptophan, which have moderate evidence for supporting mood and serotonin synthesis. Niacin and Vitamin B6 serve as essential cofactors for neurotransmitter production. Research coverage for this specific combination is limited, though the individual components are well-studied.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 70mg is 2.0× the Tolerable Upper Intake Level (35mg)

Label

Product Label

Label for MasterMind
Open Full PDF View on NIH DSLD →
Details

Label Data

4 Tablet(s)
Serving Size
30
Servings
Other Combinations
Product Type
86%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

500 mg
Market median: 200.0mg (52 products) 12 studies (A:0, B:6)
200 mg
Market median: 100.0mg (116 products) 18 studies (A:0, B:3)
1400 mg
Market median: 500.0mg (70 products)
70 mg (350% DV)
Exceeds UL by 2.0× (UL: 35 mg) 196 studies (A:5, B:63)
70 mg (3500% DV)
53.8× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
990 mcg (250% DV)
2.5× RDA — within safe limits 226 studies (A:10, B:105)
1600 mcg (26670% DV)
666.7× RDA — above typical dose 139 studies (A:1, B:44)

Other Ingredients

Stearic Acid Dicalcium Phosphate Microcrystalline Cellulose Magnesium Stearate Croscarmellose Sodium Silicon Dioxide Glyceryl Triacetate Hydroxypropyl Methyl Cellulose Pthalate Ethanol Water Titanium Dioxide
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS: 2 capsules 2 times daily with meals or as directed by a health care practitioner.

Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Zahler(R) MasterMind(TM) does NOT interfere with prescription medications and may be used simultaneously while the drugs are gradually phased out under medical supervision.

Formulation Notes

KOSHER PAREVE UNDER STRICT SUPERVISION OF RABBI SH. STERN AND THE ORTHODOX UNION

Additional Information

advanced nutrition by ZAHLER(R)

Comprehensive Antidepressant Formula

Restores Mood, Energy & Mental Balance

Restore Mood, Energy & Mental Balance Depression is caused by an imbalance in the brain's neurotransmitters (chemicals which act as the brain's messengers). However, a variety of factors, including genetic makeup, environment, physical condition, mental stressors, psychological and social factors, interact to bring on active depression.

Prevents and Alleviates: ~Major Depression ~Postpartum Depression ~Seasonal Depression ~Dysthymia ~Mood Disorders

You may need additional supplements to support a healthy diet, consult your nutritionist for a formula that is right for you, or call us toll free at 877-ASK-ZAHLER (877-275-9245)

TRIPLE CERTIFIED FORMULA

MIND & SPIRIT {capsule}

D U

STORE TIGHTLY IN COOL, DRY PLACE.

Metadata

Product Details

DSLD Entry Date2014-05-23
Product TypeOther Combinations
FormTablet or Pill
BrandZahler
DSLD ID33306
Data Updated2026-04-11
Research

Research Evidence

12
Research Sources
58
Avg Quality
8
Meta Analysis
3
Systematic Review
1
Rct
B S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2006 PubMed
B S-adenosyl methionine (SAMe) for depression in adults
Meta Analysis The Cochrane database of systematic reviews 2016 PubMed
B Systemic juvenile idiopathic arthritis and adult-onset Still's disease are the same disease: evidence from systematic reviews and meta-analyses informing the 2023 EULAR/PReS recommendations for the diagnosis and management of Still's disease
Meta Analysis Annals of the rheumatic diseases 2024 PubMed DOI
B SAMe-TT2R2 Score to Predict Time in Therapeutic Range of Vitamin K Antagonists in Asian and Non-Asian patients: A Systematic Review and Meta-analysis
Meta Analysis American journal of cardiovascular drugs : drugs, devices, and other interventions 2024 PubMed DOI
B S-Adenosylmethionine (SAMe) as an adjuvant therapy for patients with depression: An updated systematic review and meta-analysis
Meta Analysis General hospital psychiatry 2024 PubMed DOI
B S-adenosyl-L-methionine for alcoholic liver diseases
Systematic Review The Cochrane database of systematic reviews 2001 PubMed
B WITHDRAWN: S-adenosyl-L-methionine for alcoholic liver diseases
Meta Analysis The Cochrane database of systematic reviews 2015 PubMed DOI
C S-adenosyl-L-methionine for the treatment of chronic liver disease: a systematic review and meta-analysis
Meta Analysis PloS one 2015 PubMed DOI
C S-Adenosylmethionine (SAMe) for Liver Health: A Systematic Review
Systematic Review Nutrients 2024 PubMed DOI
C SAMe-TT2R2 to Predict Clinical Outcomes and Time in Therapeutic Range in Patients on Vitamin K Antagonists: A Systematic Review and Meta-Analysis
Meta Analysis The Annals of pharmacotherapy 2024 PubMed DOI
View all evidence for Same →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.