🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Vegan Capsule(s) Serving Size
21 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

25 mg (5% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 25mg UL 3500mg
100 mcg (182% DV)
✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.1mg UL 0.4mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 930mg
4'Liver
300 mg
Opitac
50 mg
Artichoke Leaf Extract
50 mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 50mg
📊 Market median: 650.0mg (87 products) 📚 1 studies — no high-quality reviews
This product: 50mg
50 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 50mg
📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)
This product: 8mg

Other Ingredients

Hypromellose Dicalcium Phosphate Stearic Acid Silica

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Doctor's suggested use: Take 2 vegan capsules once daily with a meal.

⚠️ Warnings & Precautions

Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications.

Keep out of reach of children.

🧪 Formulation Notes

Formulated by Drew Sinatra, ND Board-certified naturopathic doctor focused on integrative solutions for overall wellness whose 15 + years of treating patients - and work with supplement leader Healthy Directions - led to the development of Liver + Revive & Restore, a comprehensive formula to support daily liver health and liver function. Unconditionally guaranteed for purity and labeled potency.

Gluten free

Clinical strength Energize Detox Renew

Liver+ Revive & Restore with 4'Liver & Milk Thistle

Additional Information

Triple tested cGMP Certified Facility

Get to know the doctors at DoctorsPreferred.com 1-800-304-1709

Doctor Formulated

To preserve quality and freshness, store bottle with cap tightly closed in a cool, dry place.

Doctor Developed

Product Details

UPC / SKU 8 10047 39166 1
DSLD Entry Date 2025-02-23
Product Type Other Combinations
Form Capsule
DSLD ID 322435
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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