Home/ Supplements/ Thiamine/ Coenzyme Methyl B-Complex

Coenzyme Methyl B-Complex

product on market Capsule Nutra Sport Safety: 94/100
94/100

This product looks safe

  • Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)
  • Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)
  • 75% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This complex contains B vitamins that support energy metabolism and neurological function. There is strong clinical evidence for the roles of thiamine, riboflavin, and folate in cellular health. However, overall evidence coverage for this specific formulation is limited.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 100mg is 2.9× the Tolerable Upper Intake Level (35mg)

Folate: 400mg is 400.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Coenzyme Methyl B-Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
60
Servings
Other Combinations
Product Type
75%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

50 mg (4167% DV)
41.7× RDA — above typical dose 76 studies (A:0, B:33)
50 mg (3846% DV)
38.5× RDA — above typical dose 13 studies (A:0, B:1)
100 mg (625% DV)
Exceeds UL by 2.9× (UL: 35 mg) 196 studies (A:5, B:63)
80 mg (4706% DV)
61.5× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
400 mcg DFE (100% DV)
Exceeds UL by 400.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
500 mcg (20833% DV)
208.3× RDA — above typical dose 139 studies (A:1, B:44)
200 mcg (667% DV)
6.7× RDA — above typical dose 27 studies (A:0, B:11)
50 mg (1000% DV)
10.0× RDA — above typical dose 2 studies — no high-quality reviews
40 mg (7% DV)
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews
27 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
Protection and Support Blend
1.2 mg

Other Ingredients

Vegan Capsule Cellulose Calcium Phosphate Silica Calcium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take 2 capsules daily with food.

Warnings & Precautions

To report a serious adverse event, call 1-888-710-0006

Keep out of reach of children.

Formulation Notes

Methylated B vitamins for enhanced absorption & energy support

Our Coenzyme Methyl B-Complex contains B vitamins in the superior "active" forms to support energy production and metabolism, as well as promote healthy skin, nerves, and adrenal glands. B complex vitamins support healthy homocysteine levels for those already within a normal range. Methyl B vitamins are absorbed and utilized more efficiently by the body and are most effective when taken together. PABA is critical in folate metabolism and has been included with CoQ10 and ALA to protect and support the diverse role of B vitamins in the body.

Contains no artificial colors, flavors, or preservatives; no wheat, gluten, milk, eggs, peanuts, tree nuts, soy, crustacean shellfish or fish.

We guarantee our supplements for potency and purity

Double Verified GF Gluten free Copyright No GMO Ingredients Copyright SGS verified the process for manufacturing this product with no GMO ingredients. www.sgs.com/no-gmo

Advanced energy support

Superior form of B vitamins with 5-MTHFolate

Additional Information

Store in a cool, dry place.

Double Verified GF Gluten free Copyright No GMO Ingredients Copyright SGS verified the process for manufacturing this product with no GMO ingredients. www.sgs.com/no-gmo

Metadata

Product Details

DSLD Entry Date2024-12-21
Product TypeOther Combinations
FormCapsule
DSLD ID319219
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.