Home/ Supplements/ Thiamine/ B-Complex with CoEnzymes R5P & P5P

B-Complex with CoEnzymes R5P & P5P

product on market Capsule Kirkman Safety: 96/100
96/100

This product looks safe

  • Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)
  • 80% of ingredients have research evidence
C Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This formula contains B-vitamins that support energy metabolism and neurological function, utilizing coenzymed forms like P5P and R5P for improved bioavailability. There is strong evidence for the role of these nutrients in cellular energy production and cognitive health. The profile maintains a high safety score, indicating a low risk of adverse effects.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Folate: 333mg is 333.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B-Complex with CoEnzymes R5P & P5P
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Capsule(s)
Serving Size
100
Servings
Other Combinations
Product Type
80%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

30 mg (2500% DV)
25.0× RDA — above typical dose 76 studies (A:0, B:33)
30 mg (2308% DV)
23.1× RDA — above typical dose 13 studies (A:0, B:1)
20 mg NE (125% DV)
1.4× RDA — within safe limits 196 studies (A:5, B:63)
35 mg (2059% DV)
26.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
333 mcg DFE (83% DV)
Exceeds UL by 333.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
125 mcg (5208% DV)
52.1× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
10 mg (200% DV)
2.0× RDA — within safe limits 2 studies — no high-quality reviews
150 mg (27% DV)
Within RDA (0.3× RDA) 38 studies (A:1, B:7)
3.7 mg
Market median: 17.4mg (161 products)

Other Ingredients

Hypromellose Water Silicon Dioxide Magnesium Stearate
Claims

Label Claims — Verification

Unverified Nutrient
Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: Take two capsules daily or as directed by a physician.

Warnings & Precautions

Keep out of the reach of children. Caution: Formulated for adults and children four years and older. For children under four, consult a physician.

Formulation Notes

Free of: Milk, eggs, fish, shellfish, tree nuts, peanuts, wheat, soy, and sesame.

Hypoallergenic Supports body systems and structure

Gluten-Free

Additional Information

Important: Store in a cool dry place and tightly capped.

Ultra Tested cGMP

Metadata

Product Details

UPC / SKU8 12325 02052 2
DSLD Entry Date2024-09-25
Product TypeOther Combinations
FormCapsule
BrandKirkman
DSLD ID317691
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.