P.R.F.
98/100
This product looks safe
- Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
- 44% of ingredients have research evidence
C
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
Label Data
1 Vegetarian Capsule(s)
Serving Size
90
Servings
Botanical with Nutrients
Product Type
44%
Evidence Coverage
Supplement Facts — Evidence Check
10 mg
(821% DV)
📊 8.3× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
1 mg
(77% DV)
✅ Within RDA (0.8× RDA of 1.3 mg)
📚 12 studies (Tier A: 0, B: 1)
50 mg NE
(313% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
10 mg
(576% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
Calcium
5 mg
(1% DV)
1 mg
(5% DV)
✅ Within RDA (0.1× RDA of 11 mg)
📚 258 studies (Tier A: 6, B: 134)
Potassium
2 mg
(1% DV)
75 mg
📊 Market median: 2000.0mg (63 products)
100 mg
📊 Market median: 300.0mg (214 products)
📚 23 studies (Tier A: 0, B: 6)
📊 Market median: 250.0mg (60 products)
📚 7 studies (Tier A: 0, B: 1)
Hops Strobile Extract
13 mg
Chinese Skullcap root extract
25 mg
White Willow Bark Extract
50 mg
📊 Market median: 60.0mg (107 products)
📚 1 studies — no high-quality reviews
DL-Phenylalanine
150 mg
L-Glutamic Acid
25 mg
Other Ingredients
Silicon Dioxide
Hypromellose
Water, Purified
Label Claims — Verification
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (83% of products)
Nutrient (47% of products)
Target Groups
Vegetarian
Adult (18 - 50 Years)
Product Information
📋 Directions for Use
Recommendations: Take one (1) capsule as needed or as directed by your physician.
⚠️ Warnings & Precautions
Warning: May interact with other medications, consult your physician before use.
Children with fevers and patients with ulcers or gastritis should not take white willow bark.
If you are pregnant or breast feeding, consult your physician before using this product.
Do not exceed six (6) capsules in a 24 hour period.
Keep out of reach of children.
For professional use only.
🧪 Formulation Notes
Contains no preservatives. Bisphenol-A (BPA) & Phthalate Free
Vegetarian formulation
Non-GMO
Additional Information
Keep container tightly closed, store in a cool, dry place.
GMP Certified
Product Details
UPC / SKU
8 15354 02111 9
DSLD Entry Date
2024-10-24
Product Type
Botanical with Nutrients
Form
Capsule
DSLD ID
310770
Data Updated
2026-04-11
Research Evidence
100
Research Sources
56
Avg Quality Score
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B
Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
B
Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
B
Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
B
Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
B
Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
B
Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
B
Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
B
The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
B
Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
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