🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 85% of ingredients have research evidence
A Label Compliance Grade

Product Label

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Label Data

1 Caplet(s) Serving Size
30 Servings
Botanical with Nutrients Product Type
85% Evidence Coverage

Supplement Facts — Evidence Check

400 IU (100% DV)
✅ Within RDA (0.7× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)
RDA 0.015mg This product: 0.01mg UL 0.1mg
2 mg (133% DV)
✅ 1.7× RDA — within safe limits 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 2mg
2 mg (118% DV)
✅ 1.5× RDA — within safe limits 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 2mg
25 mg (125% DV)
✅ 1.8× RDA — within safe limits 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 25mg UL 35mg
10 mg (500% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
50 mcg (833% DV)
📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.05mg
75 mcg (50% DV)
✅ Within RDA (0.5× RDA of 0.15 mg) 📚 243 studies (Tier A: 4, B: 133)
RDA 0.15mg This product: 0.075mg UL 1.1mg
150 mg (38% DV)
📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)
This product: 150mg
10 mg (67% DV)
✅ Within RDA (0.9× RDA of 11 mg) 📚 258 studies (Tier A: 6, B: 134)
RDA 11mg This product: 10mg UL 40mg
2 mg (100% DV)
✅ 2.2× RDA — within safe limits 📚 36 studies (Tier A: 0, B: 11)
RDA 0.9mg This product: 2mg UL 10mg
60 mcg (50% DV)
✅ 1.7× RDA — within safe limits 📚 197 studies (Tier A: 1, B: 55)
RDA 0.035mg This product: 0.06mg
Hormone Balance and Circulatory Support
Strong Bone and Circulatory Support

Other Ingredients

Dicalcium Phosphate Cellulose Safflower Oil Titanium Dioxide Riboflavin natural Vanilla flavor Vegetable Acetoglycerides Carmine Sucralose

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (85% of products) Nutrient (70% of products) Approved Health (4% of products)

Target Groups

Menopause Seniors/Mature (>50 Years) - Women ONLY Gluten Free

Product Information

📋 Directions for Use

Directions: As a dietary supplement, take one caplet twice daily. For maximum support, take as directed every day.

To ensure a complete nutritional program, take daily with these GNC products: Women's Ultra Mega(R) 50+ Multivitamin Triple Strength Fish Oil + GLA Ultra Probiotic Complex 30 Women's Protein

⚠️ Warnings & Precautions

KEEP OUT OF REACH OF CHILDREN.

Discontinue use two weeks prior to surgery.

CONTAINS: Milk

WARNING: Do not use if pregnant or nursing. Consult your physician prior to using this product if you are taking medication or have a medical condition.

🧪 Formulation Notes

Hormone Balance Blend - Combines a potent blend that includes Sophora japonica fruit extract, which has been clinically for its role in menopause support, with traditional black cohosh and hops standardized to provide additional support. This formula also contains ultra-concentrated GLA, a prostaglandin precursor essential in the regulation of hormone balance, as well as the circulatory, nervous and immune systems.

Strong Bone & Circulatory Support Complex - In addition to the well-known benefits of vitamin D in supporting calcium absorption and bone health, this formula also contains MBP(R), a unique clinically efficacious active protein complex that supports a woman's biological ability to build and maintain healthy bone mass. In addition, it features 120 mg of high quality Ginkgo biloba which may help to improve memory function and increase peripheral blood flow for improved cardiovascular health.

Energy & Metabolism Management Matrix - Key vitamins and minerals including chromium and iodine were each carefully selected to work cooperatively with a woman's body assisting in cellular energy production and other molecular activities such as the metabolism of dietary carbohydrate, fat and protein.

No Artificial Colors, No Artificial Flavors, No Wheat, No Gluten, No Soy, Yeast Free.

CONTAINS: Milk

Additional Information

NEW

DEVELOPED WITH AND ENDORSED BY GNC MEDICAL ADVISORY BOARD ADVANCED KNOWLEDGE FOR BETTER HEALTH THE GNC Medical Advisory Board utilizes their in-depth medical knowledge and experience to aid in the creation and ongoing development of GNC products, helping GNC stay on the forefront of product innovation and delivering on our commitment to helping you LIVE WELL.

GNC QUALITY COMMITMENT For more than 77 years, GNC has been the leader in the development of superior nutritional supplements. Our products are produced using only fresh, high-quality ingredients and are manufactured under the strictest quality control.

Store in a cool, dry place.

Each premium formula is designed to be used on conjunction with your physician recommended healthcare regimen. This line of products is precisely formulated to provide clinical strength ingredients and additional nutrients that address key health concerns.

This comprehensive formula helps support a wide spectrum of menopausal concerns such as hot flashes, night sweats, mood swings, bone density loss, forgetfulness and decreased arousal.

Glucose utilization, lipid profile balance, red blood cell production and DNA repair all require adequate levels of the essential nutrients found in the Menopause Support Formula.

PHYSICIAN FORMULATED NUTRITION SOLUTIONS Clinically studied menopause support Provides key nutrients to support hormone levels & healthy metabolism Improves bone density & maximizes calcium absorption

PHYSICIAN ENDORSED

MBP(R)

CODE 187712 LOG

Omniflavone(TM) SOPHORA JAPONICA EXTRACT

Product Details

DSLD Entry Date 2014-03-25
Product Type Botanical with Nutrients
Form Unknown
DSLD ID 31054
Data Updated 2026-04-11

Research Evidence

872 Research Sources
53 Avg Quality Score
309 Meta Analysis
309 Clinical Trial
111 Rct
71 Systematic Review
55 Guideline
4 Cochrane Review
4 Regulatory Source
2 Other
2 Narrative Review
2 Observational
1 Openfda Safety
A Vitamin D and vitamin D analogues for preventing fractures associated with involutional and post-menopausal osteoporosis
Meta Analysis The Cochrane database of systematic reviews 2009
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D and vitamin D analogues for preventing fractures in post-menopausal women and older men
Meta Analysis The Cochrane database of systematic reviews 2014
A Vitamin D supplementation for prevention of cancer in adults
Meta Analysis The Cochrane database of systematic reviews 2014
A Interventions for preventing falls in older people in care facilities and hospitals
Meta Analysis The Cochrane database of systematic reviews 2018
A Drugs for preventing lung cancer in healthy people
Meta Analysis The Cochrane database of systematic reviews 2020
A Vitamin D supplementation for prevention of mortality in adults
Meta Analysis The Cochrane database of systematic reviews 2011
A High prevalence of vitamin D deficiency in Asia: A systematic review and meta-analysis
Meta Analysis Critical reviews in food science and nutrition 2023
A The effect of vitamin D supplementation on depressive symptoms in adults: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Critical reviews in food science and nutrition 2023
A Interventions for preventing falls in older people living in the community
Meta Analysis The Cochrane database of systematic reviews 2009
View all evidence for Vitamin D →

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