🟢 100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 50% of ingredients have research evidence
A Label Compliance Grade

Product Label

📸

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Label Data

2 Vegan Capsule(s) Serving Size
30 Servings
Other Combinations Product Type
50% Evidence Coverage

Supplement Facts — Evidence Check

25 mg (5% DV)
📊 Market median: 125.0mg (294 products) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 25mg UL 3500mg
100 mcg (182% DV)
✅ 1.8× RDA — within safe limits 📚 172 studies (Tier A: 0, B: 67)
RDA 0.055mg This product: 0.1mg UL 0.4mg
📊 Market median: 250.0mg (562 products) 📚 53 studies (Tier A: 0, B: 19)
This product: 930mg
4'Liver
300 mg
Opitac
50 mg
Artichoke Leaf Extract
50 mg
📊 Market median: 300.0mg (159 products)
Median 300.0mg This product: 50mg
📊 Market median: 650.0mg (87 products) 📚 1 studies — no high-quality reviews
This product: 50mg
50 mg
📊 Market median: 500.0mg (283 products) 📚 173 studies (Tier A: 0, B: 62)
This product: 50mg
📊 Market median: 167.0mg (311 products) 📚 182 studies (Tier A: 0, B: 65)
This product: 8mg

Other Ingredients

Hypromellose Dicalcium Phosphate Stearic Acid Silica

Label Claims — Verification

All Other
Structure/Function
All Other (97% of products) Structure/Function (90% of products) Nutrient (42% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free

Product Information

📋 Directions for Use

Doctor's suggested use: Take 2 vegan capsules once daily with a meal.

⚠️ Warnings & Precautions

Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications.

Keep out of reach of children.

🧪 Formulation Notes

Unconditionally guaranteed for purity and labeled potency.

Gluten free

Clinical strength Energize Detox Renew

Liver+ Revive & Restore with 4'Liver & Milk Thistle

Additional Information

Formulated by Drew Sinatra, ND Board-certified naturopathic doctor focused on integrative solutions for overall wellness whose 15 + years of treating patients - and work with supplement leader Healthy Directions - led to the development of Liver + Revive & Restore, a comprehensive formula to support daily liver health and liver function.

Get to know the doctors at DoctorsPreferred.com

Doctor Formulated

To preserve quality and freshness, store bottle with cap tightly closed in a cool, dry place.

Doctor developed

Triple tested cGMP Certified Facility

Product Details

UPC / SKU 8 10047 39155 5
DSLD Entry Date 2024-05-23
Product Type Other Combinations
Form Capsule
DSLD ID 309898
Data Updated 2026-04-11

Research Evidence

28 Research Sources
47 Avg Quality Score
11 Clinical Trial
8 Rct
2 Guideline
2 Meta Analysis
2 Regulatory Source
1 Systematic Review
1 Openfda Safety
B Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis Biological psychiatry. Cognitive neuroscience and neuroimaging 2024
B Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline Briefings in bioinformatics 2026
B Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline Journal of gastroenterology 2022
B Scientific Opinion on health claims related to choline
Regulatory Source EFSA Journal 2011
C Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis Nutrition reviews 2022
C Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct The American journal of clinical nutrition
C Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct The American journal of clinical nutrition
C Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review Psychotherapy and psychosomatics 2013
C The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct The British journal of nutrition 2007
C Differential metabolism of choline supplements in adult volunteers.
Rct European journal of nutrition
View all evidence for Choline →

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