100/100
This product looks safe
- No ingredients exceed tolerable upper intake levels
- 50% of ingredients have research evidence
A
Label Compliance Grade
What the Evidence Says
✨ AI-generated · Qwen 3.6
· methodology
This formula contains milk thistle and choline, which have moderate evidence for supporting liver function and lipid metabolism. Selenium provides antioxidant support, though overall evidence coverage for this specific combination is limited. The profile maintains a high safety score with no significant concerns noted.
AI-generated summary based on research evidence. Not medical advice.
Details
Label Data
2 Vegan Capsule(s)
Serving Size
Other Combinations
Product Type
Ingredients
Supplement Facts — Evidence Check
Market median: 125.0mg (294 products)
38 studies (A:1, B:7)
1.8× RDA — within safe limits
173 studies (A:0, B:67)
Market median: 250.0mg (562 products)
55 studies (A:0, B:19)
Artichoke Leaf Extract
50 mg
Market median: 300.0mg (159 products)
Market median: 650.0mg (87 products)
1 studies — no high-quality reviews
Market median: 500.0mg (283 products)
174 studies (A:0, B:62)
Market median: 167.0mg (311 products)
183 studies (A:0, B:65)
Other Ingredients
Hypromellose
Dicalcium Phosphate
Stearic Acid
Silica
Claims
Label Claims — Verification
Unverified
All Other
Unverified
Structure/Function
Info
Product Information
Directions for Use
Doctor's suggested use: Take 2 vegan capsules once daily with a meal.
Warnings & Precautions
Precautions: Consult a health care practitioner before use if you are pregnant or nursing, have a serious medical condition, or use any medications.
Keep out of reach of children.
Formulation Notes
Unconditionally guaranteed for purity and labeled potency.
Gluten free
Clinical strength
Energize
Detox
Renew
Liver+ Revive & Restore with 4'Liver & Milk Thistle
Additional Information
Formulated by Drew Sinatra, ND
Board-certified naturopathic doctor focused on integrative solutions for overall wellness whose 15 + years of treating patients - and work with supplement leader Healthy Directions - led to the development of Liver + Revive & Restore, a comprehensive formula to support daily liver health and liver function.
Get to know the doctors at DoctorsPreferred.com
Doctor Formulated
To preserve quality and freshness, store bottle with cap tightly closed in a cool, dry place.
Doctor developed
Triple tested
cGMP Certified Facility
Metadata
Product Details
UPC / SKU8 10047 39155 5
DSLD Entry Date2024-05-23
Product TypeOther Combinations
FormCapsule
Data Updated2026-04-11
Research
Research Evidence
B
Greater Choline-Containing Compounds and Myo-inositol in Treatment-Resistant Versus Responsive Schizophrenia: A 1H-Magnetic Resonance Spectroscopy Meta-analysis
Meta Analysis
Biological psychiatry. Cognitive neuroscience and neuroimaging
2024
PubMed
DOI
B
Integrating multi-structure covalent docking with machine-learning consensus scoring enhances potency ranking of human acetylcholinesterase inhibitors.
Guideline
Briefings in bioinformatics
2026
PubMed
DOI
B
Evidence-based clinical practice guidelines for functional dyspepsia 2021.
Guideline
Journal of gastroenterology
2022
PubMed
DOI
B
Scientific Opinion on health claims related to choline
Regulatory Source
EFSA Journal
2011
DOI
C
Effectiveness of nutritional interventions to prevent nonprogressive congenital and perinatal brain injuries: a systematic review and meta-analysis of randomized trials
Meta Analysis
Nutrition reviews
2022
PubMed
DOI
C
Two methods for assessment of choline status in a randomized crossover study with varying dietary choline intake in people: isotope dilution MS of plasma and in vivo single-voxel magnetic resonance spectroscopy of liver.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Choline and betaine concentrations in plasma discriminate levels of dietary choline intake in healthy adults: analysis of a double-blind randomized crossover controlled feeding study.
Rct
The American journal of clinical nutrition
PubMed
DOI
C
Nutrient-based therapies for bipolar disorder: a systematic review
Systematic Review
Psychotherapy and psychosomatics
2013
PubMed
DOI
C
The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people
Rct
The British journal of nutrition
2007
PubMed
C
Differential metabolism of choline supplements in adult volunteers.
View all evidence for Choline →
This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.
