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B-125 Complex

product on market Tablet or Pill Swanson Safety: 90/100
90/100

This product looks safe

  • Niacinamide: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)
  • Vitamin B6: 125mg is 1.2× the Tolerable Upper Intake Level (100mg)
  • Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)
  • 82% of ingredients have research evidence
F Label Compliance Grade

What the Evidence Says

✨ AI-generated · Qwen 3.6 · methodology

This complex contains B vitamins that support energy metabolism and neurological function. There is strong evidence for the roles of thiamine, folate, and B6 in cellular health. The formulation maintains a high safety profile for general use.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacinamide: 125mg is 3.6× the Tolerable Upper Intake Level (35mg)

Vitamin B6: 125mg is 1.2× the Tolerable Upper Intake Level (100mg)

Folate: 665mg is 665.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for B-125 Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
100
Servings
Other Combinations
Product Type
82%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

125 mg (10417% DV)
104.2× RDA — above typical dose 76 studies (A:0, B:33)
125 mg (9615% DV)
96.2× RDA — above typical dose 13 studies (A:0, B:1)
125 mg NE (781% DV)
Exceeds UL by 3.6× (UL: 35 mg) 196 studies (A:5, B:63)
125 mg (7353% DV)
Exceeds UL by 1.2× (UL: 100 mg) 114 studies (A:3, B:35)
665 mcg DFE (166% DV)
Exceeds UL by 665.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
125 mcg (5208% DV)
52.1× RDA — above typical dose 139 studies (A:1, B:44)
125 mcg (417% DV)
4.2× RDA — above typical dose 27 studies (A:0, B:11)
125 mg (2500% DV)
25.0× RDA — above typical dose 2 studies — no high-quality reviews
Within RDA (0.2× RDA) 38 studies (A:1, B:7)
125 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
125 mg
Market median: 500.0mg (9 products) 7 studies — no high-quality reviews

Other Ingredients

Stearic Acid Dicalcium Phosphate Croscarmellose Sodium Magnesium Stearate Silica Hydroxypropyl Methylcellulose Glycerin Hydroxypropyl Cellulose
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested use: As a dietary supplement, take one tablet per day with water.

Warnings & Precautions

Warning: For adults only. Keep out of reach of children.

Consult your physician before using this or any product if you are pregnant or nursing, taking medication or have a medical condition.

Do not use if seal is broken.

Formulation Notes

Promotes nervous system, immune and cardiovascular health Protects against stress-induced nutrient depletion

Energy and nervous system health Higher potency

Additional Information

Store in a cool, dry place.

Metadata

Product Details

UPC / SKU0 87614 11688 4
DSLD Entry Date2024-10-24
Product TypeOther Combinations
FormTablet or Pill
BrandSwanson
DSLD ID308805
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
View all evidence for Thiamine →
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.