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Osteo Bi-Flex Joint & Energy

product on market Other (e.g. tea bag) Osteo Bi-Flex Safety: 100/100
100/100

This product looks safe

  • No ingredients exceed tolerable upper intake levels
  • 53% of ingredients have research evidence
A Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

This formula contains Vitamin C and D, which have strong evidence for supporting immune function and bone health. Thiamine contributes to energy metabolism through essential biochemical pathways. Overall, these ingredients are well-supported by research for general nutritional maintenance.

AI-generated summary based on research evidence. Not medical advice.

Label

Product Label

Label for Osteo Bi-Flex Joint & Energy
Open Full PDF View on NIH DSLD →
Details

Label Data

2 Caplet(s)
Serving Size
40
Servings
Other Combinations
Product Type
53%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

Calories
10 {Calories}
Total Carbohydrates
2 Gram(s) (1% DV)
Vitamin C
60 mg (100% DV)
200 IU (50% DV)
Within RDA (0.3× RDA) 608 studies (A:16, B:251)
1 mg (67% DV)
Within RDA (0.8× RDA) 76 studies (A:0, B:33)
1 mg (59% DV)
Within RDA (0.8× RDA) 13 studies (A:0, B:1)
2 mg (100% DV)
1.5× RDA — within safe limits 114 studies (A:3, B:35)
25 mcg (417% DV)
10.4× RDA — above typical dose 139 studies (A:1, B:44)
2 mg (100% DV)
Within RDA (0.9× RDA) 9 studies — no high-quality reviews
Sodium
40 mg (2% DV)
1500 mg
Market median: 1000.0mg (1115 products) 24 studies (A:0, B:9)
Joint Shield(TM) Proprietary Blend
1104 mg
Within RDA (0.1× RDA) 38 studies (A:1, B:7)
50 mg
Market median: 550.0mg (217 products) 29 studies (A:0, B:5)
3 mg
Market median: 3.0mg (58 products) 3 studies — no high-quality reviews

Other Ingredients

Cellulose Crospovidone Contains Less Than 2% of
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

DIRECTIONS FOR ADULT USE: TAKE TWO (2) CAPLETS PER DAY PREFERABLY WITH FOOD.

Warnings & Precautions

CAUTION: Not intended for use by pregnant or nursing women. If you are taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Not intended for use by persons under the age of 18.

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

KEEP OUT OF REACH OF CHILDREN.

TAMPER RESISTANT: DO NOT USE IF SEAL UNDER CAP IS BROKEN OR MISSING.

Formulation Notes

Free of Gluten

Contains shellfish (shrimp, crab, lobster, crayfish) ingredients.

It contains 1,500 mg of Glucosamine, a key building block of cartilage.* With the addition of our Joint Shield(TM) Proprietary Blend, which contains Chondroitin, MSM and 5-LOXIN(R) Advanced, this revolutionary Energy Formula helps support energy metabolism and revitalize your joints to keep them jumpin’.*

GLUCOSAMINE CHONDROITIN PLUS JOINT SHIELD(TM)

With 5-LOXIN(R) ADVANCED

Additional Information

Proud sponsor of the ARTHRITIS FOUNDATION(R)

52399 00A B52399 MAB

#Based on two human studies with 5-LOXIN(R) Advanced where subjects rated their joint health over time, subjects’ joint health improved within 7 days, and continued to improve throughout the duration of the studies.

**52 week Nielsen ScanTrack data ending 8/25/12.

Part No. 22-52399

HELPS REVITALIZE YOUR JOINTS* KEY BUILDING BLOCK OF CARTILAGE*

2 PER DAY

STORE AT ROOM TEMPERATURE AND AVOID EXCESSIVE HEAT.

SUPPORT ENERGY METABOLISM

#1 DOCTOR & PHARMACIST RECOMMENDED BRAND^

As a reminder, discuss the supplements and medications you take with your health care providers.

PROUD SPONSOR of the ARTHRITIS FOUNDATION(R) Rexall Sundown, Inc., the maker of Osteo Bi-Flex(R), is proud to support the Arthritis Foundation's efforts to help people take control of arthritis. For information about arthritis, contact the Foundation at 1-800-568-4045 or www.arthritis.org

NEW! SMOOTH WHITE COATING SAME FORMULA

The natural aging process can add excessive stress on your joints. Annoying flare-ups can strike at any time. Add Osteo Bi-Flex(R) Joint & Energy to your joint care regimen.

Starts working to improve joint comfort within 7 days.*#

Osteo Bi-Flex(R) is manufactured under the highest standards for product quality, purity and potency.

^Based on the results of a GfK Healthcare 2011 survey among physicians who recommend a brand of Glucosamine and Chondroitin or Glucosamine supplements; and the result of a Pharmacy Times Survey among pharmacists who recommend a “bone/joint strengthener” dietary supplement, 2006-2012.

Metadata

Product Details

UPC / SKU0 30768 18870 2
DSLD Entry Date2014-02-26
Product TypeOther Combinations
FormOther (e.g. tea bag)
DSLD ID30801
Data Updated2026-04-11
Research

Research Evidence

371
Research Sources
54
Avg Quality
148
Meta Analysis
82
Systematic Review
71
Rct
62
Clinical Trial
2
Regulatory Source
1
Cochrane Review
1
Narrative Review
1
Other
1
Openfda Safety
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Meta Analysis BMC medicine 2021 PubMed DOI
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.