B-Complex by NOW — Ingredients, Evidence & Safety

🟢 93/100

This product looks safe

Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)
82% of ingredients have research evidence

D Label Compliance Grade

Product Label

📄 Open Full PDF View on NIH DSLD →

📸

Have a supplement label? Find it here.

Upload a photo of any supplement label to search our database of 92,312 products.

Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)

⚠️ Folate: 680mg is 680.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size

250 Servings

Other Combinations Product Type

82% Evidence Coverage

Supplement Facts — Evidence Check

Thiamine

50 mg (4167% DV)

📊 41.7× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)

RDA 1.2mg This product: 50mg

Riboflavin

50 mg (3846% DV)

📊 38.5× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)

RDA 1.3mg This product: 50mg

Niacin

50 mg (313% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)

RDA 14mg This product: 50mg UL 35mg

Vitamin B6

20 mg (1176% DV)

📊 15.4× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 20mg UL 100mg

Folate

680 mcg DFE (170% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 680.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 680mg UL 1.0mg

Vitamin B12

50 mcg (2083% DV)

📊 20.8× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.05mg

Biotin

50 mcg (167% DV)

✅ 1.7× RDA — within safe limits 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.05mg

Pantothenic Acid

50 mg (1000% DV)

📊 10.0× RDA — above typical dose 📚 1 studies — no high-quality reviews

RDA 5mg This product: 50mg

Choline

50 mg (9% DV)

✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)

RDA 550mg This product: 50mg UL 3500mg

Para-Aminobenzoic Acid

50 mg

📊 Market median: 500.0mg (9 products)

This product: 50mg

Inositol

50 mg

📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)

This product: 50mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Croscarmellose Sodium Magnesium Stearate Silicon Dioxide

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegan Vegetarian Adult (18 - 50 Years) Gluten Free Dairy Free

Product Information

📋 Directions for Use

Suggested Usage: Take 1 tablet daily with a meal.

⚠️ Warnings & Precautions

Caution: For adults only. Keep out of reach of children.

Consult physician if pregnant/nursing, taking medication, or have a medical condition.

This product contains Biotin which may interfere with some blood test results. Go to nowfoods.com/biotinlab for details.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

🧪 Formulation Notes

This product provides a full complement of B-vitamins plus choline and inositol. These vitamins work to support energy production, maintain healthy homocysteine metabolism, and promote the health of the nervous system. B-vitamins are water soluble, and with the exception of B-12, have limited storage in the body and thus require daily replenishment. While B-12 is stored in the liver, dietary sources are of animal origin only (meat and dairy) and supplementation with B-12 may be especially important for vegetarians.

Natural color variation may occur in this product.

Nervous System Heath Supports Energy Production

B-Complex for Maximum Effectiveness

Non-GMO

Vegetarian/Vegan

Made and quality tested in the USA with globally sourced ingredients.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish, tree nut or sesame ingredients.

Additional Information

Store in a cool, dry place after opening.

GMP Quality Assured

Vitamins Family owned since 1968.

Product Details

UPC / SKU 7 33739 90428 7

DSLD Entry Date 2024-01-24

Product Type Other Combinations

Form Tablet or Pill

Brand NOW

DSLD ID 303908

Data Updated 2026-04-11

Research Evidence

100 Research Sources

56 Avg Quality Score

48 Systematic Review

30 Meta Analysis

13 Rct

6 Clinical Trial

1 Cochrane Review

1 Regulatory Source

B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol

Systematic Review The Cochrane database of systematic reviews 2013

PubMed DOI Cochrane

B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials

Systematic Review Nutritional neuroscience 2023

PubMed DOI

B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis

Meta Analysis BMJ open 2022

PubMed DOI

B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024

PubMed DOI

B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis

Systematic Review Intensive care medicine 2022

PubMed DOI

B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis

Meta Analysis Pain medicine (Malden, Mass.) 2020

PubMed DOI

B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis

Meta Analysis Critical care medicine 2021

PubMed DOI

B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Complementary therapies in medicine 2022

PubMed DOI

B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis

Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023

PubMed DOI

B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse

Systematic Review The Cochrane database of systematic reviews 2004

PubMed Cochrane

View all evidence for Thiamine →