🟢 93/100

This product looks safe

  • Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
  • Folate: 167mg is 167.0× the Tolerable Upper Intake Level (1.0mg)
  • 82% of ingredients have research evidence
D Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Niacin: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 167mg is 167.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

1 Tablet(s) Serving Size
90 Servings
Other Combinations Product Type
82% Evidence Coverage

Supplement Facts — Evidence Check

10 mg (833% DV)
📊 8.3× RDA — above typical dose 📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg This product: 10mg
10 mg (769% DV)
📊 7.7× RDA — above typical dose 📚 12 studies (Tier A: 0, B: 1)
RDA 1.3mg This product: 10mg
50 mg (313% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg) 📚 193 studies (Tier A: 5, B: 63)
RDA 14mg This product: 50mg UL 35mg
10 mg (588% DV)
📊 7.7× RDA — above typical dose (UL: 100 mg) 📚 113 studies (Tier A: 3, B: 35)
RDA 1.3mg This product: 10mg UL 100mg
167 mcg DFE (42% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 167.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)
RDA 0.4mg This product: 167mg UL 1.0mg
10 mcg (417% DV)
📊 4.2× RDA — above typical dose 📚 138 studies (Tier A: 1, B: 44)
RDA 0.0024mg This product: 0.01mg
20 mcg (67% DV)
✅ Within RDA (0.7× RDA of 0.03 mg) 📚 26 studies (Tier A: 0, B: 11)
RDA 0.03mg This product: 0.02mg
15 mg (300% DV)
✅ 3.0× RDA — within safe limits 📚 1 studies — no high-quality reviews
RDA 5mg This product: 15mg
50 mg (9% DV)
✅ Within RDA (0.1× RDA of 550 mg) 📚 36 studies (Tier A: 1, B: 7)
RDA 550mg This product: 50mg UL 3500mg
50 mg
📊 Market median: 550.0mg (217 products) 📚 29 studies (Tier A: 0, B: 5)
This product: 50mg
📊 Market median: 500.0mg (9 products)
This product: 10mg

Other Ingredients

Microcrystalline Cellulose Stearic Acid Cellulose Rice Bran Magnesium Stearate Pharmaceutical Glaze

Label Claims — Verification

All Other
Structure/Function
All Other (99% of products) Structure/Function (83% of products) Nutrient (47% of products)

Target Groups

Vegetarian Adult (18 - 50 Years) No Allergies Gluten Free

Product Information

📋 Directions for Use

Directions: One tablet daily, preferably with or directly after a meal.

⚠️ Warnings & Precautions

Keep out of reach of children.

🧪 Formulation Notes

Free from artificial colors and artificial preservatives. Free from all the major allergens identified in the U.S. Food Allergen Labeling and Consumer Protection Act.

Vegetarian

Gluten free

Energy support

Additional Information

Keep tightly closed in a cool, dry place.

Product Details

UPC / SKU 0 97467 01480 0
DSLD Entry Date 2023-10-24
Product Type Other Combinations
Form Tablet or Pill
DSLD ID 298655
Data Updated 2026-04-11

Research Evidence

100 Research Sources
56 Avg Quality Score
48 Systematic Review
30 Meta Analysis
13 Rct
6 Clinical Trial
1 Cochrane Review
1 Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004
View all evidence for Thiamine →

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