Immune 24 Hour + by Nature's Bounty — Ingredients, Evidence & Safety

🟢 98/100

This product looks safe

Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
62% of ingredients have research evidence

C Label Compliance Grade

Product Label

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Safety Alerts

⚠️ Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)

Label Data

2 Softgel(s) Serving Size

25 Servings

Botanical with Nutrients Product Type

62% Evidence Coverage

Supplement Facts — Evidence Check

Calories

20 Calorie(s)

Total Fat

1 Gram(s) (1% DV)

Total Carbohydrates

2 Gram(s) (1% DV)

Vitamin A

750 mcg (83% DV)

Ester-C

1000 mg (1111% DV)

Vitamin D

15 mcg (75% DV)

✅ Within RDA (1.0× RDA of 0.015 mg) 📚 604 studies (Tier A: 16, B: 251)

RDA 0.015mg This product: 0.015mg UL 0.1mg

Vitamin B6

2 mg (118% DV)

✅ 1.5× RDA — within safe limits 📚 113 studies (Tier A: 3, B: 35)

RDA 1.3mg This product: 2mg UL 100mg

Folate

666 mcg DFE (167% DV)

⚠️ Exceeds Tolerable Upper Intake Level by 666.0× (UL: 1.0 mg) 📚 225 studies (Tier A: 10, B: 105)

RDA 0.4mg This product: 666mg UL 1.0mg

Vitamin B12

6 mcg (250% DV)

✅ 2.5× RDA — within safe limits 📚 138 studies (Tier A: 1, B: 44)

RDA 0.0024mg This product: 0.006mg

Biotin

300 mcg (1000% DV)

📊 10.0× RDA — above typical dose 📚 26 studies (Tier A: 0, B: 11)

RDA 0.03mg This product: 0.3mg

Pantothenic Acid

10 mg (200% DV)

✅ 2.0× RDA — within safe limits 📚 1 studies — no high-quality reviews

RDA 5mg This product: 10mg

Magnesium

25 mg (6% DV)

📊 Market median: 4002.0mg (1 products) 📚 20 studies (Tier A: 0, B: 2)

This product: 25mg

Zinc

15 mg (136% DV)

✅ 1.4× RDA — within safe limits 📚 258 studies (Tier A: 6, B: 134)

RDA 11mg This product: 15mg UL 40mg

Elderberry

17 mg

📊 Market median: 175.0mg (497 products) 📚 11 studies (Tier A: 0, B: 1)

This product: 17mg

Echinacea

16.5 mg

📊 Market median: 400.0mg (380 products) 📚 34 studies (Tier A: 1, B: 10)

This product: 16.5mg

Astragalus

16.5 mg

📊 Market median: 470.0mg (230 products) 📚 9 studies (Tier A: 3, B: 3)

This product: 16.5mg

Other Ingredients

Rice Bran Oil Gelatin Glycerin Carob, Powder natural Caramel color Sunflower Lecithin yellow Beeswax

Label Claims — Verification

❓ Nutrient

❓ All Other

❓ Structure/Function

All Other (99% of products) Structure/Function (76% of products) Nutrient (58% of products)

Target Groups

Adult (18 - 50 Years) Gluten Free Sugar Free

Product Information

📋 Directions for Use

Directions: For adults, take two (2) softgels daily, preferably with a meal.

⚠️ Warnings & Precautions

Warning: if you are pregnant, nursing, taking any medications, have any medical condition, or are planning to undergo any clinical lab testing, consult your doctor before use. Some supplements may interact with certain medications and/or interfere with certain lab tests.

Avoid this product if you are allergic to sunflowers or daisy-like flowers.

Discontinue use if any adverse reactions occur.

Not intended for use by persons under the age of 18. Keep out of reach of children.

Do not use if seal under cap is broken or missing.

🧪 Formulation Notes

1000mg Ester-C per serving

The only vitamin C with 24 hour immune support Supports upper respiratory health

Non-GMO No gluten No artificial flavor No artificial sweetener No sugar

1000 mg Ester-C per serving + Vitamin D & Zinc With elderberry, echinacea

Additional Information

Store at room temperature.

Nutrition questions or comments? Call 1-800-433-2990 Mon. - Sat. 9 AM - 7 PM ET Sign up for news and offers at NaturesBounty.com

Product Details

UPC / SKU 0 74312 00809 2

DSLD Entry Date 2023-06-22

Product Type Botanical with Nutrients

Form Softgel Capsule

Brand Nature's Bounty

DSLD ID 296182

Data Updated 2026-04-11

Research Evidence

337 Research Sources

54 Avg Quality Score

161 Meta Analysis

68 Systematic Review

51 Rct

48 Clinical Trial

2 Other

2 Regulatory Source

1 Narrative Review

1 Cochrane Review

1 Guideline

1 Openfda Safety

A Vitamin A supplementation for preventing morbidity and mortality in children from six months to five years of age

Meta Analysis The Cochrane database of systematic reviews 2017

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants six months of age or less

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplementation for reducing the risk of mother-to-child transmission of HIV infection

Meta Analysis The Cochrane database of systematic reviews 2011

PubMed DOI Cochrane

A Vitamin A supplements for preventing mortality, illness, and blindness in children aged under 5: systematic review and meta-analysis

Meta Analysis BMJ (Clinical research ed.) 2011

PubMed DOI

A Fortification of staple foods with vitamin A for vitamin A deficiency

Systematic Review The Cochrane database of systematic reviews 2019

PubMed DOI Cochrane

A Vitamin A supplementation for the prevention of morbidity and mortality in infants one to six months of age

Narrative Review The Cochrane database of systematic reviews 2016

PubMed DOI Cochrane

A Vitamin A and fish oils for preventing the progression of retinitis pigmentosa

Meta Analysis The Cochrane database of systematic reviews 2020

PubMed DOI

A Exercise training-induced changes in exerkine concentrations may be relevant to the metabolic control of type 2 diabetes mellitus patients: A systematic review and meta-analysis of randomized controlled trials

Meta Analysis Journal of sport and health science 2023

PubMed DOI

A Food fortification with multiple micronutrients: impact on health outcomes in general population

Meta Analysis The Cochrane database of systematic reviews 2019

PubMed DOI

A Oral vitamin A supplements to prevent acute upper respiratory tract infections in children up to seven years of age

Meta Analysis The Cochrane database of systematic reviews 2024

PubMed DOI

View all evidence for Vitamin A →