What the Evidence Says
✨ AI-generated · Qwen 3.6
· methodology
This complex provides essential B vitamins, including thiamine, riboflavin, and folate, which support energy metabolism and neurological function. There is strong evidence for the role of these nutrients in maintaining cellular health and cognitive processes. The formulation maintains a high safety profile for general supplementation.
AI-generated summary based on research evidence. Not medical advice.
Safety Alerts
⚠️ Niacinamide: 50mg is 1.4× the Tolerable Upper Intake Level (35mg)
Label Data
1 Tablet(s)
Serving Size
50
Servings
Other Combinations
Product Type
82%
Evidence Coverage
Supplement Facts — Evidence Check
📊 41.7× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
RDA 1.2mg
This product: 50mg
📊 38.5× RDA — above typical dose
📚 13 studies (Tier A: 0, B: 1)
RDA 1.3mg
This product: 50mg
⚠️ Exceeds Tolerable Upper Intake Level by 1.4× (UL: 35 mg)
📚 196 studies (Tier A: 5, B: 63)
RDA 14mg
This product: 50mg
UL 35mg
📊 38.5× RDA — above typical dose (UL: 100 mg)
📚 114 studies (Tier A: 3, B: 35)
RDA 1.3mg
This product: 50mg
UL 100mg
✅ 2.0× RDA — within safe limits
📚 226 studies (Tier A: 10, B: 105)
RDA 0.4mg
This product: 0.8mg
UL 1.0mg
📊 20.8× RDA — above typical dose
📚 139 studies (Tier A: 1, B: 44)
RDA 0.0024mg
This product: 0.05mg
✅ 1.7× RDA — within safe limits
📚 27 studies (Tier A: 0, B: 11)
RDA 0.03mg
This product: 0.05mg
📊 20.0× RDA — above typical dose
📚 2 studies — no high-quality reviews
RDA 5mg
This product: 100mg
✅ Within RDA (0.1× RDA of 550 mg)
📚 38 studies (Tier A: 1, B: 7)
RDA 550mg
This product: 50mg
UL 3500mg
📊 Market median: 550.0mg (217 products)
📚 29 studies (Tier A: 0, B: 5)
📊 Market median: 500.0mg (9 products)
📚 7 studies — no high-quality reviews
Other Ingredients
Sorbitol
Stearic Acid
Silica
Modified Cellulose Gum
Magnesium Sterate
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (83% of products)
Nutrient (47% of products)
Target Groups
Adult (18 - 50 Years)
Product Information
📋 Directions for Use
Suggested Use: 1 to 2 tablets daily.
⚠️ Warnings & Precautions
Note: If you are pregnant, may become pregnant, or breastfeeding, consult your health care professional before using this product.
Do not use if either tamper-evident seal is broken or missing.
Keep out of the reach of children.
🧪 Formulation Notes
Supports energy production
B-vitamins are essential components of numerous key enzyme systems, without which the body cannot function. Each B-vitamin fills a different complementary need, which is why they should most often be taken together. B-vitamins act as coenzymes to catalyze numerous biochemical reactions.
Product Details
UPC / SKU
0 21078 00420 2
DSLD Entry Date
2023-06-22
Product Type
Other Combinations
Form
Tablet or Pill
Data Updated
2026-04-11
Research Evidence
100
Research Sources
56
Avg Quality Score
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
Systematic Review
The Cochrane database of systematic reviews
2013
Systematic Review
Nutritional neuroscience
2023
Meta Analysis
BMJ open
2022
Meta Analysis
Clinical nutrition (Edinburgh, Scotland)
2024
Systematic Review
Intensive care medicine
2022
Meta Analysis
Pain medicine (Malden, Mass.)
2020
Meta Analysis
Critical care medicine
2021
Meta Analysis
Complementary therapies in medicine
2022
Meta Analysis
Clinical and investigative medicine. Medecine clinique et experimentale
2023
Systematic Review
The Cochrane database of systematic reviews
2004
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