Home/ Supplements/ Thiamine/ Fermented Coenzyme B Complex

Fermented Coenzyme B Complex

product on market Tablet or Pill New Chapter Safety: 94/100
94/100

This product looks safe

  • Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)
  • Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)
  • 69% of ingredients have research evidence
D Label Compliance Grade

What the Evidence Says

AI-generated · Qwen 3.6 · methodology

The B-vitamin complex, including thiamine, riboflavin, and folate, supports cellular energy metabolism and neurological function. Research provides strong evidence for the role of these nutrients in maintaining metabolic health. The formulation maintains a high safety profile with minimal reported concerns.

AI-generated summary based on research evidence. Not medical advice.

Alerts

Safety Alerts

Niacin: 45mg is 1.3× the Tolerable Upper Intake Level (35mg)

Folate: 666mg is 666.0× the Tolerable Upper Intake Level (1.0mg)

Label

Product Label

Label for Fermented Coenzyme B Complex
Open Full PDF View on NIH DSLD →
Details

Label Data

1 Tablet(s)
Serving Size
90
Servings
Botanical with Nutrients
Product Type
69%
Evidence Coverage
Ingredients

Supplement Facts — Evidence Check

5 mg (417% DV)
4.2× RDA — above typical dose 76 studies (A:0, B:33)
3.9 mg (300% DV)
3.0× RDA — within safe limits 13 studies (A:0, B:1)
45 mg (281% DV)
Exceeds UL by 1.3× (UL: 35 mg) 196 studies (A:5, B:63)
9 mg (529% DV)
6.9× RDA — above typical dose (UL: 100 mg) 114 studies (A:3, B:35)
666 mcg DFE (167% DV)
Exceeds UL by 666.0× (UL: 1.0 mg) 226 studies (A:10, B:105)
120 mcg (5000% DV)
50.0× RDA — above typical dose 139 studies (A:1, B:44)
300 mcg (1000% DV)
10.0× RDA — above typical dose 27 studies (A:0, B:11)
45 mg (900% DV)
9.0× RDA — above typical dose 2 studies — no high-quality reviews
Stress and Energy Support Blend
150 mg
Cardio Support Blend
60 mg
Immune Support Blend
56.2 mg
7 mg
Market median: 450.0mg (254 products) 243 studies (A:0, B:100)
Market median: 250.0mg (337 products) 127 studies (A:1, B:41)

Other Ingredients

Soy Flour Saccharomyces cerevisiae Orange, Powder Alfalfa, Powder Lactobacillus acidophilus Bifidobacterium bifidum Lactobacillus rhamnosus Papain Bromelain Gum Acacia Silica Lac Resin Carnauba Wax
Claims

Label Claims — Verification

Unverified All Other
Unverified Structure/Function
Info

Product Information

Directions for Use

Suggested Use: One tablet daily. Can be taken anytime, even on an empty stomach.

Warnings & Precautions

Caution: As with any dietary supplement, you should advise your healthcare professional of the use of this product if you have a medical condition or take medication. If you are nursing, pregnant, or considering pregnancy, consult your healthcare professional prior to using this product.

Keep out of reach of children.

Contains: Fermented soy.

Formulation Notes

Certified gluten-free by NSF; 100% vegetarian; No artificial flavors or colors.

Certified gluten-free by NSF; 100% vegetarian; No artificial flavors or colors.

Formulated for absorption Energy & nervous system support

Made with organic vegetables & herbs

Non GMO Project Verified nongmoproject.org NSF Certified Gluten-free

OU (Kosher)

Certified Organic by International Certification Services, Inc., Meidna, ND, USA

Additional Information

The New Chapter Money-Back Guarantee We proudly stand behind every product we make. However, if you are not satisfied, please visit www.newchapter.com/guarantee for refund details. Please recycle this bottle after use.

ICS (International Certification Services) Non GMO Project Verified nongmoproject.org NSF Certified Gluten-free OU (Kosher)

Metadata

Product Details

DSLD Entry Date2023-04-21
Product TypeBotanical with Nutrients
FormTablet or Pill
DSLD ID288193
Data Updated2026-04-11
Research

Research Evidence

100
Research Sources
56
Avg Quality
48
Systematic Review
30
Meta Analysis
13
Rct
6
Clinical Trial
1
Cochrane Review
1
Regulatory Source
B Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol
Systematic Review The Cochrane database of systematic reviews 2013 PubMed DOI
B Efficacy of B-vitamins and vitamin D therapy in improving depressive and anxiety disorders: a systematic review of randomized controlled trials
Systematic Review Nutritional neuroscience 2023 PubMed DOI
B Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis
Meta Analysis BMJ open 2022 PubMed DOI
B Effect of intravenous thiamine administration on critically ill patients: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Clinical nutrition (Edinburgh, Scotland) 2024 PubMed DOI
B Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock: a systematic review and a component network meta-analysis
Systematic Review Intensive care medicine 2022 PubMed DOI
B Effect of Combined Diclofenac and B Vitamins (Thiamine, Pyridoxine, and Cyanocobalamin) for Low Back Pain Management: Systematic Review and Meta-analysis
Meta Analysis Pain medicine (Malden, Mass.) 2020 PubMed DOI
B Thiamine, Ascorbic Acid, and Hydrocortisone As a Metabolic Resuscitation Cocktail in Sepsis: A Meta-Analysis of Randomized Controlled Trials With Trial Sequential Analysis
Meta Analysis Critical care medicine 2021 PubMed DOI
B The effects of thiamine supplementation on patients with heart failure: A systematic review and meta-analysis of randomized controlled trials
Meta Analysis Complementary therapies in medicine 2022 PubMed DOI
B Hydrocortisone Combined with Vitamin C and Thiamine in the Treatment of Sepsis/Septic Shock: A Systematic Review with Meta-Analysis and Trial Sequential Analysis
Meta Analysis Clinical and investigative medicine. Medecine clinique et experimentale 2023 PubMed DOI
B Thiamine for Wernicke-Korsakoff Syndrome in people at risk from alcohol abuse
Systematic Review The Cochrane database of systematic reviews 2004 PubMed
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This product page is for informational purposes only and does not constitute medical advice. Always consult your healthcare provider before taking any supplement.