B-Complex with Metafolin L-5-MTHF
90/100
This product looks safe
- Niacin: 108mg is 3.1× the Tolerable Upper Intake Level (35mg)
- Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
- 88% of ingredients have research evidence
D
Label Compliance Grade
Product Label
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Safety Alerts
⚠️ Niacin: 108mg is 3.1× the Tolerable Upper Intake Level (35mg)
⚠️ Folate: 667mg is 667.0× the Tolerable Upper Intake Level (1.0mg)
Label Data
1 Vegetarian Capsule(s)
Serving Size
60
Servings
Vitamin
Product Type
88%
Evidence Coverage
Supplement Facts — Evidence Check
100 mg
(8333% DV)
📊 83.3× RDA — above typical dose
📚 76 studies (Tier A: 0, B: 33)
12.7 mg
(977% DV)
📊 9.8× RDA — above typical dose
📚 12 studies (Tier A: 0, B: 1)
108 mg
(675% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 3.1× (UL: 35 mg)
📚 193 studies (Tier A: 5, B: 63)
16.7 mg
(982% DV)
📊 12.8× RDA — above typical dose (UL: 100 mg)
📚 113 studies (Tier A: 3, B: 35)
667 mcg DFE
(167% DV)
⚠️ Exceeds Tolerable Upper Intake Level by 667.0× (UL: 1.0 mg)
📚 225 studies (Tier A: 10, B: 105)
400 mcg
(16667% DV)
📊 166.7× RDA — above typical dose
📚 138 studies (Tier A: 1, B: 44)
400 mcg
(1333% DV)
📊 13.3× RDA — above typical dose
📚 26 studies (Tier A: 0, B: 11)
100 mg
(2000% DV)
📊 20.0× RDA — above typical dose
📚 1 studies — no high-quality reviews
Other Ingredients
Hydroxypropyl Methylcellulose
Ascorbyl Palmitate
Label Claims — Verification
❓
Nutrient
❓
All Other
❓
Structure/Function
All Other (99% of products)
Structure/Function (77% of products)
Nutrient (60% of products)
Approved Health (5% of products)
Target Groups
Adult (18 - 50 Years)
Gluten Free
Product Information
📋 Directions for Use
Suggested Usage: As a dietary supplement, adults take 1 capsule,1-2 times daily, or as directed by your health professional.
⚠️ Warnings & Precautions
Warning: If you are pregnant, nursing, have any health condition or taking any medication, consult your health professional before using this product.
Keep out of the reach of children.
Use only if safety seal is intact.
🧪 Formulation Notes
Gluten-free, Non-GMO
Energy metabolism and neurological health
Additional Information
Store in a cool, dry place.
Scan to learn about our manufacturing excellence Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.
Product Details
UPC / SKU
3 10539 98018 7
DSLD Entry Date
2022-09-22
Product Type
Vitamin
Form
Capsule
Brand
Douglas Laboratories
DSLD ID
274136
Data Updated
2026-04-11
Research Evidence
363
Research Sources
57
Avg Quality Score
187
Meta Analysis
56
Systematic Review
54
Rct
29
Guideline
26
Clinical Trial
6
Cochrane Review
2
Regulatory Source
1
Other
1
Openfda Safety
A
Community-based intervention packages for reducing maternal and neonatal morbidity and mortality and improving neonatal outcomes
A
Folate Intake and Risk of Pancreatic Cancer: A Systematic Review and Updated Meta-Analysis of Epidemiological Studies
A
The Association Between the Risk of Hypertensive Disorders of Pregnancy and Folic Acid: A Systematic Review and Meta-Analysis
A
A Comparative Study Evaluating the Effectiveness of Folate-Based B Vitamin Intervention on Cognitive Function of Older Adults under Mandatory Folic Acid Fortification Policy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
A
Associations between serum Homocysteine, vitamin B9, and vitamin B12 levels and the formation of intracranial Aneurysms: A systematic review and meta-analysis
A
Intake of vitamin B6, folate, and vitamin B12 and risk of coronary heart disease: a systematic review and dose-response meta-analysis of prospective cohort studies
A
Beneficial effects of folic acid supplementation on lipid markers in adults: A GRADE-assessed systematic review and dose-response meta-analysis of data from 21,787 participants in 34 randomized controlled trials
A
Folic acid supplementation and blood pressure: a GRADE-assessed systematic review and dose-response meta-analysis of 41,633 participants
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